6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one

Base Information

Chemical Name:6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one
CAS No.:68415-20-3
Molecular Formula:C14H16N4O4
Molecular Weight:304.305
Hs Code.:
DSSTox Substance ID:DTXSID10498757
Nikkaji Number:J457.254H
Wikidata:Q82349016

Synonyms:68415-20-3;SCHEMBL10760147;DTXSID10498757;6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one

Suppliers and Price of 6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:304.11715500
Heavy Atom Count:22
Complexity:470

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(=O)NN=C1C2=CC(=C(C=C2)N3CCOCC3)[N+](=O)[O-]

Technology Process of 6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one

There total 3 articles about 6-[4-(Morpholin-4-yl)-3-nitrophenyl]-4,5-dihydropyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42564-51-2
4-fluoro-3-nitrobenzaldehyde

: 68415-20-3
6-(4-morpholin-4-yl-3-nitro-phenyl)-4,5-dihydro-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: TsOH

2: (i) KOH, EtOH, (ii) N₂H₄*H₂O

With toluene-4-sulfonic acid;

Reference yield:

: 56872-65-2
3-(3-nitro-4-morpholino-benzoyl)-propionic acid

: 68415-20-3
6-(4-morpholin-4-yl-3-nitro-phenyl)-4,5-dihydro-2H-pyridazin-3-one

Guidance literature:: With hydrazine hydrate; In ethanol; for 2h; Heating;
DOI:10.1016/0223-5234(91)90121-3

Reference yield:

: 84314-04-5
4-(4-chloro-3-nitrophenyl)-4-oxobutanoic acid

: 68415-20-3
6-(4-morpholin-4-yl-3-nitro-phenyl)-4,5-dihydro-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / iPr₂NEt / dimethylsulfoxide / 3 h / 80 °C

2: H₂NNH₂*H₂O / ethanol / 2 h / Heating

With hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In ethanol; dimethyl sulfoxide;
DOI:10.1016/0223-5234(91)90121-3