3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione

Base Information

Chemical Name:3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione
CAS No.:68724-84-5
Molecular Formula:C12H10N2O2
Molecular Weight:214.224
Hs Code.:
DSSTox Substance ID:DTXSID60436664
Nikkaji Number:J701.980G
Wikidata:Q82251945
ChEMBL ID:CHEMBL2088745
Mol file:68724-84-5.mol

Synonyms:68724-84-5;3,4-Dihydroazepino[3,4-b]indole-1,5(2H,10H)-dione;starbld0001613;3,4-DIHYDRO-2H,10H-AZEPINO[3,4-B]INDOLE-1,5-DIONE;2,3,4,10-tetrahydroazepino[3,4-b]indole-1,5-dione;SCHEMBL3427648;CHEMBL2088745;DTXSID60436664;AG-G-65567;2,3-Dihydroazepino[3,4-b]indole-1,5(4H,10H)-dione

Suppliers and Price of 3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Dihydro-2H,10H-azepino[3,4-b]indole-1,5-dione
10mg
$ 335.00

Medical Isotopes, Inc.
3,4-Dihydro-2H,10H-azepino[3,4-β]indole-1,5-dione
25 mg
$ 2000.00

American Custom Chemicals Corporation
3,4-DIHYDRO-2H,10H-AZEPINO[3,4-B]INDOLE-1,5-DIONE 95.00%
50MG
$ 1758.49

American Custom Chemicals Corporation
3,4-DIHYDRO-2H,10H-AZEPINO[3,4-B]INDOLE-1,5-DIONE 95.00%
5MG
$ 730.54

AccelPharmtech
3,4-dihydro-Azepino[3,4-b]indole-1,5(2H,10H)-dione 97.00%
25G
$ 4010.00

AccelPharmtech
3,4-dihydro-Azepino[3,4-b]indole-1,5(2H,10H)-dione 97.00%
5G
$ 2180.00

AccelPharmtech
3,4-dihydro-Azepino[3,4-b]indole-1,5(2H,10H)-dione 97.00%
1G
$ 1940.00

Total 16 raw suppliers

Chemical Property of 3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:603.389oC at 760 mmHg
Flash Point:318.719oC
PSA：61.96000
Density:1.378g/cm3
LogP:1.81290
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:214.074227566
Heavy Atom Count:16
Complexity:329

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

3,4-Dihydro-2H,10H-azepino[3,4-b]indole-1,5-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC(=O)C2=C(C1=O)C3=CC=CC=C3N2
Uses A myt1 kinase inhibitor for the treatment of cancer and proliferative diseases 3,4-Dihydro-2H,10H-azepino[3,4-b]indole-1,5-dione Methanesulfonate Salt is a myt1 kinase inhibitor.

Technology Process of 3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione

There total 7 articles about 3,4-Dihydro-2H,10H-azepino[3,4-B]indole-1,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 68724-79-8
3-[(1H-indole-2-carbonyl)amino]propionic acid

: 68724-84-5
3,4-dihydroazepino[3,4-b]indole-1,5-(2H,10H)-dione

Guidance literature:: With methanesulfonic acid; phosphorus pentoxide; at 110 ℃; for 1.5h;
DOI:10.1021/jm040013d

Reference yield: 75.0%

: 1221227-25-3
C₂₃H₂₅F₃N₂O₈S

: 68724-84-5
3,4-dihydroazepino[3,4-b]indole-1,5-(2H,10H)-dione

Guidance literature:: C₂₃H₂₅F₃N₂O₈S; With fur-2-ylboronic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; sodium carbonate; In ethanol; toluene; at 70 ℃; Inert atmosphere;

With silica gel; at 100 ℃; for 1h; Inert atmosphere;
DOI:10.1055/s-0029-1218573