Technology Process of Carbamic acid, (1R,3R,4S)-1-azabicyclo[2.2.1]hept-3-yl-, 1,1-dimethylethyl
There total 4 articles about Carbamic acid, (1R,3R,4S)-1-azabicyclo[2.2.1]hept-3-yl-, 1,1-dimethylethyl which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
for 48h;
under 2585.74 Torr;
DOI:10.1016/j.bmc.2006.09.019
- Guidance literature:
-
trans-3-(tert-butoxycarbonylamino)-4-(2-hydroxyethyl)-1-(N-phenylmethyl)pyrrolidine;
With
methanesulfonyl chloride; triethylamine;
In
dichloromethane;
In
ethanol;
for 16h;
Heating / reflux;
With
hydrogen;
palladium 10% on activated carbon;
at 20 ℃;
under 2740.96 Torr;
- Guidance literature:
-
trans (tert-butoxycarbonylamino)-exo-4-R-(2-hydroxyethyl)-1-(N-phenylmethyl)-3-pyrrolidine;
With
methanesulfonyl chloride; triethylamine;
In
dichloromethane;
at 0 ℃;
for 0.166667h;
With
hydrogen;
palladium 10% on activated carbon;
In
ethanol;
under 2740.96 Torr;