6,7-Dimethoxyisoquinoline-1-carbonitrile

Base Information

Chemical Name:6,7-Dimethoxyisoquinoline-1-carbonitrile
CAS No.:68881-60-7
Molecular Formula:C12H10N2O2
Molecular Weight:214.224
Hs Code.:
DSSTox Substance ID:DTXSID20498309
Wikidata:Q82348289

Synonyms:6,7-dimethoxyisoquinoline-1-carbonitrile;68881-60-7;Oprea1_111938;DTXSID20498309

Suppliers and Price of 6,7-Dimethoxyisoquinoline-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6,7-Dimethoxyisoquinoline-1-carbonitrile

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:214.074227566
Heavy Atom Count:16
Complexity:286

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(=C1)C=CN=C2C#N)OC

Technology Process of 6,7-Dimethoxyisoquinoline-1-carbonitrile

There total 8 articles about 6,7-Dimethoxyisoquinoline-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: (2RS,3RS,11bSR)-2-bromomethyl-3-ethyl-9,10-dimethoxy-1,2,3,6,7,11b-hexahydro-4H-benzo[a]quinolizin-4-one

: 50299-95-1,35096-40-3
2-benzoyl-1-cyano-6,7-dimethoxy-1,2-dihydroisoquinoline

: (2SR,3RS,11bSR)-2-benzoyl-1-(3-ethyl-9,10-dimethoxy-4-oxo-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizin-2-ylmethyl)-6,7-dimethoxy-1,2-dihydroisoquinoline-1-carbonitrile

: 68881-60-7
6,7-dimethoxyisoquinoline-1-carbonitrile

: 20359-09-5
(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)(phenyl)methanone

Guidance literature:: 2-benzoyl-1-cyano-6,7-dimethoxy-1,2-dihydroisoquinoline; With sodium hydride; In N,N-dimethyl-formamide;

(2RS,3RS,11bSR)-2-bromomethyl-3-ethyl-9,10-dimethoxy-1,2,3,6,7,11b-hexahydro-4H-benzo[a]quinolizin-4-one; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Further stages.;
DOI:10.1007/s00706-007-0601-x

Reference yield: 55.0%

: 112450-88-1
6,7-Dimethoxy-2-benzoyl-1-diphenylmethyl-1-cyano-1,2-dihydroisochinolin

: 68881-60-7
6,7-dimethoxyisoquinoline-1-carbonitrile

: 112450-91-6
6,7-Dimethoxy-1-diphenylmethyl-isochinolin

Guidance literature:: With N-benzyl-trimethylammonium hydroxide; In methanol; N,N-dimethyl-formamide; at 30 ℃; for 3h;
DOI:10.1002/ardp.19873200405