1-Propanone, 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-

Base Information

• Chemical Name: 1-Propanone, 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-
• CAS No.: 69100-73-8
• Molecular Formula: C17H15N3O
• Molecular Weight: 277.32100
• Mol file: 69100-73-8.mol

Synonyms:1,3-diphenyl-3-[1,2,4]triazol-1-yl-propan-1-one;1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)propan-1-one;(phenyl)-[2-phenyl-2-(1,2,4-triazol-1-yl)ethyl]-ketone;1,3-Diphenyl-3-[1,2,4]triazol-1-yl-propan-1-on;

Chemical Property of 1-Propanone, 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-

Chemical Property:

• Melting Point: 77 - 78 °C
• PSA: 47.78000
• LogP: 3.14050

Purity/Quality:

1,3-DIPHENYL-3-(1,2,4-TRIAZOL-1-YL)PROPAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Propanone, 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-

There total 5 articles about 1-Propanone, 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

1,2,4-Triazole (288-88-0) + 1,3-diphenyl-propen-3-one (614-47-1) → 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-1-propanone (69100-73-8)

Guidance literature:

at 120 ℃; for 6h; Heating / reflux;

Reference yield: 58.0%

1,2,4-Triazole (288-88-0) + 1,3-diphenyl-1-propyn-3-ol (1817-49-8) → 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-1-propanone (69100-73-8)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; toluene; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c2ob25165e

Reference yield: 30.0%

1,1'-thiocarbonylbis(1,2,4-triazole) (63976-76-1) + 1,3-diphenyl-propen-3-one (614-47-1) → 1,3-diphenyl-3-(1H-1,2,4-triazol-1-yl)-1-propanone (69100-73-8) + phenyl(6-phenyl[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)methanone

Guidance literature:

In toluene; at 90 ℃;

DOI:10.1021/ol990370w

upstream raw materials:

1,2,4-Triazole

1,3-diphenyl-propen-3-one

1,1'-thiocarbonylbis(1,2,4-triazole)

1,3-diphenyl-1-propyn-3-ol