1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one

Base Information

Chemical Name:1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one
CAS No.:86456-17-9
Molecular Formula:C19H22N2O3
Molecular Weight:326.3896
Hs Code.:
NSC Number:355185
DSSTox Substance ID:DTXSID70320121
Wikidata:Q82077042

Synonyms:NSC 355185;86456-17-9;1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one;1-{[2-(Diethylamino)ethyl]amino}-7-hydroxy-9H-xanthen-9-one;NSC355185;SCHEMBL11002059;DTXSID70320121;NSC-355185

Suppliers and Price of 1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one

Chemical Property:

Vapor Pressure:9.32E-12mmHg at 25°C
Boiling Point:527.8°Cat760mmHg
Flash Point:273°C
Density:1.249g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:326.16304257
Heavy Atom Count:24
Complexity:427

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCNC1=C2C(=CC=C1)OC3=C(C2=O)C=C(C=C3)O

Technology Process of 1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one

There total 5 articles about 1-((2-(Diethylamino)ethyl)amino)-7-hydroxy-9H-xanthen-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 86456-15-7
1-<<2-(diethylamino)ethyl>amino>-7-methoxy-9H-xanthen-9-one

: 86456-17-9
1-<<2-(diethylamino)ethyl>amino>-7-hydroxy-9H-xanthen-9-one

Guidance literature:: With hydrogen iodide; for 4h; Heating;
DOI:10.1021/jm00363a007

Reference yield:

: 6563-60-6
methoxy-9H-xanthen-9-one

: 86456-17-9
1-<<2-(diethylamino)ethyl>amino>-7-hydroxy-9H-xanthen-9-one

Guidance literature:: With sodium hydroxide; HI; In water;

Reference yield:

: 625-99-0
3-iodochlorobenzene

: 86456-17-9
1-<<2-(diethylamino)ethyl>amino>-7-hydroxy-9H-xanthen-9-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) K₂CO₃, 2.) Cu, CuI / 1.) DMF, 120 deg C, 10 min, 2.) DMF, reflux, 50 h

2: 1.) 50percent polyphosphoric acid, 2.) pyridine / 1.) 120 deg C, 3 h, 2.) reflux, 16 h

3: 86 percent / 56percent HI / 4 h / Heating

With pyridine; copper(l) iodide; PPA; hydrogen iodide; copper; potassium carbonate;
DOI:10.1021/jm00363a007