3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole

Base Information

Chemical Name:3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole
CAS No.:694434-08-7
Molecular Formula:C₁₁H₁₃NO
Molecular Weight:175.23
Hs Code.:
DSSTox Substance ID:DTXSID80580996
Nikkaji Number:J1.824.981B
Wikidata:Q82472008
Mol file:694434-08-7.mol

Synonyms:3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole;694434-08-7;SCHEMBL14085315;DTXSID80580996;AKOS017531980;CS-0225613;EN300-124437;1H-Pyrrole,2,5-dihydro-3-(4-methoxyphenyl)-(9CI);Z1262616902

Suppliers and Price of 3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
3-(4-Methoxyphenyl)-2,5-dihydro-1H-pyrrole
2.5g
$ 1988.00

AK Scientific
3-(4-Methoxyphenyl)-2,5-dihydro-1H-pyrrole
500mg
$ 851.00

Total 3 raw suppliers

Chemical Property of 3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole

Chemical Property:

PSA：21.26000
LogP:2.01060
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:192

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Methoxyphenyl)-2,5-dihydro-1H-pyrrole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CCNC2

Technology Process of 3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole

There total 2 articles about 3-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₆H₂₃NO₄

: 694434-08-7
3-(4-methoxy-phenyl)-2,5-dihydro-1H-pyrrole

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1039/c4ob02009j

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 694434-08-7
3-(4-methoxy-phenyl)-2,5-dihydro-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C

1.2: Cooling

2.1: trifluoroacetic acid / dichloromethane / 20 °C

With n-butyllithium; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1039/c4ob02009j