2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride

Base Information

Chemical Name:2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride
CAS No.:91417-86-6
Molecular Formula:C₁₂H₁₄N₂O₂*ClH
Molecular Weight:254.716
Hs Code.:

Synonyms:2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride;1-Carboxymethyl-2-(N-phenylimino)pyrrolidine hydrochloride;1-Pyrrolidineacetic acid, 2-(phenylimino)-, monohydrochloride;91417-86-6;AKOS024341384;LS-137145;(2-(PHENYLIMINO)-1-PYRROLIDINYL)ACETIC ACID HYDROCHLORIDE

Suppliers and Price of 2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride

Chemical Property:

Vapor Pressure:5.21E-07mmHg at 25°C
Boiling Point:396.8°Cat760mmHg
Flash Point:193.8°C
Density:g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:254.0822054
Heavy Atom Count:17
Complexity:283

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=NC2=CC=CC=C2)N(C1)CC(=O)O.Cl

Technology Process of 2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride

There total 5 articles about 2-(Phenylimino)-1-pyrrolidineacetic acid monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 91417-93-5
1-Cyanomethyl-2-(N-phenylimino)pyrrolidine

: 91417-86-6
1-Carboxymethyl-2-(N-phenylimino)pyrrolidine hydrochloride

Guidance literature:: With hydrogenchloride; for 24h; Ambient temperature;
DOI:10.1007/BF00758995

Reference yield:

: 57275-83-9
nitrile of 2-oxopyrrolidine-1-acetic acid

: 91417-86-6
1-Carboxymethyl-2-(N-phenylimino)pyrrolidine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) POCl₃ / 1.) benzene, room temp., 4.5 h, 2.) EtOH, 0.5 h

2: 89 percent / 1.) benzene, room temp., 4.5 h, 2.) reflux, 45 min

3: 98 percent / conc. aq. HCl / 24 h / Ambient temperature

With hydrogenchloride; trichlorophosphate;
DOI:10.1007/BF00758995

Reference yield:

: 7491-74-9
2-oxo-1-pyrrolidine acetamide

: 91417-86-6
1-Carboxymethyl-2-(N-phenylimino)pyrrolidine hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) POCl₃, DMF, 2.) pyridine / 1.) acetonitrile, 50 deg C, 2.5 h, 2.) 0 deg C, 20 min

2: 1.) POCl₃ / 1.) benzene, room temp., 4.5 h, 2.) EtOH, 0.5 h

3: 89 percent / 1.) benzene, room temp., 4.5 h, 2.) reflux, 45 min

4: 98 percent / conc. aq. HCl / 24 h / Ambient temperature

With pyridine; hydrogenchloride; N,N-dimethyl-formamide; trichlorophosphate;
DOI:10.1007/BF00758995