Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

Technology Process of aquastatin A

aquastatin A

Base Information
  • Chemical Name:aquastatin A
  • CAS No.:153821-50-2
  • Molecular Formula:C36H52 O12
  • Molecular Weight:676.79
  • Hs Code.:
  • Mol file:153821-50-2.mol
aquastatin A

Synonyms:AquastatinA

Suppliers and Price of aquastatin A
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 3 raw suppliers
Chemical Property of aquastatin A
Chemical Property:
  • Vapor Pressure:1.08E-29mmHg at 25°C 
  • Boiling Point:836.5°C at 760 mmHg 
  • PKA:2.60±0.25(Predicted) 
  • Flash Point:254.5°C 
  • PSA：227.26000 
  • Density:1.269g/cm3 
  • LogP:8.92170 
Purity/Quality:

95% *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
Refernces

Aquastatin C, a new glycoaromatic derivative from Sporothrix sp. FN611

10.1038/ja.2010.156

The research aims to investigate a new compound, Aquastatin C, derived from the fungal strain Sporothrix sp. FN611, for its potential as an antibacterial agent. The study focuses on bacterial fatty acid synthesis (FAS), a process crucial for bacterial cell membrane formation and a promising target for antibacterial drugs due to its differences between bacterial and mammalian systems. The researchers isolated Aquastatin C through a series of chemical processes, including ethyl acetate extraction, silica gel column chromatography, and HPLC purification. They determined its structure using NMR spectroscopy and other analytical techniques. The study found that Aquastatin C, unlike its precursor Aquastatin A, does not inhibit bacterial enoyl-ACP reductase enzymes (FabI, FabK, and InhA) or show antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus, and Streptococcus pneumoniae. This suggests that the 2-hydroxy-6-methyl benzoic acid ring, absent in Aquastatin C, is essential for the inhibitory activity of Aquastatin A. The findings provide insights into the structure-activity relationship of these compounds, highlighting the importance of specific structural features for their antibacterial efficacy.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 153821-50-2

Total 8 Pictures about this product