4,4'-Dimethoxybenzhydryl bromide

Base Information

• Chemical Name: 4,4'-Dimethoxybenzhydryl bromide
• CAS No.: 69545-37-5
• Molecular Formula: C15H15BrO2
• Molecular Weight: 307.187
• DSSTox Substance ID: DTXSID40549145
• Nikkaji Number: J1.506.803E
• Wikidata: Q82428076
• Mol file: 69545-37-5.mol

Synonyms:69545-37-5;4,4'-Dimethoxybenzhydryl bromide;4,4'-(bromomethylene)bis(methoxybenzene);Benzene, 1,1'-(bromomethylene)bis[4-methoxy-;1-[bromo-(4-methoxyphenyl)methyl]-4-methoxybenzene;SCHEMBL119132;DTXSID40549145;KMMVASCGYGKYEI-UHFFFAOYSA-N;1,1'-(Bromomethylene)bis(4-methoxybenzene);CS-0091901;D75265

Chemical Property of 4,4'-Dimethoxybenzhydryl bromide

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 306.02554
• Heavy Atom Count: 18
• Complexity: 207

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)Br

Technology Process of 4,4'-Dimethoxybenzhydryl bromide

There total 16 articles about 4,4'-Dimethoxybenzhydryl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4,4'-Dimethoxybenzhydrol (728-87-0) → di(p-anisyl)methyl bromide (69545-37-5)

Guidance literature:

With Acetyl bromide; In toluene; at 0 - 25 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmc.2018.05.049

Reference yield:

bis(p-methoxyphenyl)methyl cation (46835-92-1) → di(p-anisyl)methyl bromide (69545-37-5)

Guidance literature:

With tetrabutylammomium bromide; In acetonitrile; at 20 ℃; Rate constant;

DOI:10.1021/ja00020a038

Reference yield:

bis-(4-methoxyphenyl)methyl acetate (42240-30-2) → di(p-anisyl)methyl bromide (69545-37-5)

Guidance literature:

With tetrabutylammomium bromide; In ethanol; water; at 20 ℃; Further Variations:; Solvents; Kinetics; Flash photolysis;

DOI:10.1021/ja045562n

upstream raw materials:

4,4'-Dimethoxybenzhydrol

bis(p-methoxyphenyl)methyl cation

bis-(4-methoxyphenyl)methyl acetate

bis(4-methoxyphenyl)methyl 4-cyanophenyl ether

Downstream raw materials:

(3S)-(+)-1-di(p-anisyl)methyl-7-chloro-1,3-dihydro-3-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

(11aR)-(+)-11a-allyl-10-di(p-anisyl)methyl-2,3,5,10,11,11a-hexahydro-5,11-dioxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine

(3R)-(+)-3-allyl-1-di(p-anisyl)methyl-7-chloro-1,3-dihydro-3-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one

(11aR)-(+)-10-di(p-anisyl)methyl-11a-benzyl-2,3,5,10,11,11a-hexahydro-5,11-dioxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine