Benzyl 2-hydroxypiperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 2-hydroxypiperidine-1-carboxylate
CAS No.:69622-67-9
Molecular Formula:C13H17NO3
Molecular Weight:235.283
Hs Code.:
European Community (EC) Number:690-687-9
Nikkaji Number:J1.165.654D
Mol file:69622-67-9.mol

Synonyms:Benzyl 2-hydroxypiperidine-1-carboxylate;2-Hydroxy-piperidine-1-carboxylic acid benzyl ester;69622-67-9;SCHEMBL5326054;1-(Benzyloxycarbonyl)piperidine-2-ol;2-Hydroxypiperidine-1-carboxylic acid benzyl ester

Suppliers and Price of Benzyl 2-hydroxypiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
2-Hydroxy-piperidine-1-carboxylicacidbenzylester ＞95%
1 G
$ 450.00

Total 2 raw suppliers

Chemical Property of Benzyl 2-hydroxypiperidine-1-carboxylate

Chemical Property:

Boiling Point:384.9±42.0 °C(Predicted)
PKA:13.89±0.20(Predicted)
PSA：49.77000
Density:1.220±0.06 g/cm3(Predicted)
LogP:2.06540
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:235.12084340
Heavy Atom Count:17
Complexity:251

Purity/Quality:

98% ^*data from raw suppliers

2-Hydroxy-piperidine-1-carboxylicacidbenzylester ＞95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(C(C1)O)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 2-hydroxypiperidine-1-carboxylate

There total 16 articles about Benzyl 2-hydroxypiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.17%

: 106412-35-5
N-benzyloxycarbonyl-2-piperidone

: 69622-67-9
benzyl 2-hydroxypiperidine-1-carboxylate

Guidance literature:: With diisobutylaluminium hydride; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.6b03463

Reference yield: 92.0%

: 3742-91-4
N-(benzyloxycarbonyl)piperidine

: 69622-67-9
benzyl 2-hydroxypiperidine-1-carboxylate

Guidance literature:: With tetraethylammonium p-tosylate; In water; acetonitrile; at 3 ℃; Electrochemical reaction;
DOI:10.1055/s-2008-1072658

Reference yield: 91.0%

: 28697-07-6
N-benzyloxycarbonyl D/L-pipecolinic acid

: 69622-67-9
benzyl 2-hydroxypiperidine-1-carboxylate

Guidance literature:: With sodium tetrahydroborate; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; oxygen; caesium carbonate; In dichloromethane; at 40 ℃; for 40h; Irradiation;
DOI:10.1021/acs.joc.0c00312