N-Phenyl-N'-propan-2-ylsulfuric diamide

Base Information

• Chemical Name: N-Phenyl-N'-propan-2-ylsulfuric diamide
• CAS No.: 69705-83-5
• Molecular Formula: C9H14N2O2S
• Molecular Weight: 214.288
• DSSTox Substance ID: DTXSID30500644
• Wikidata: Q82352417
• Mol file: 69705-83-5.mol

Synonyms:N-Phenyl-N'-propan-2-ylsulfuric diamide;69705-83-5;SCHEMBL8312186;DTXSID30500644

Chemical Property of N-Phenyl-N'-propan-2-ylsulfuric diamide

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 214.07759887
• Heavy Atom Count: 14
• Complexity: 251

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NS(=O)(=O)NC1=CC=CC=C1

Technology Process of N-Phenyl-N'-propan-2-ylsulfuric diamide

There total 3 articles about N-Phenyl-N'-propan-2-ylsulfuric diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-phenyl-2-oxooxazolidine-3-sulfonamide (87708-16-5) + isopropylamine (75-31-0) → N-isopropyl-N'-phenyl-sulfamide (69705-83-5)

Guidance literature:

In acetonitrile; at 20 - 40 ℃; for 2h;

DOI:10.1021/op0600106

Reference yield: 80.0%

C9H13IN2O2S → N-isopropyl-N'-phenyl-sulfamide (69705-83-5)

Guidance literature:

C₉H₁₃IN₂O₂S; With methylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 1h;

With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃; for 0.5h;

With cyclopentanone; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/S0040-4039(00)01778-0

Reference yield:

→ N-isopropyl-N'-phenyl-sulfamide (69705-83-5)

Guidance literature:

Anilin, iso-Propylsulfamoylchlorid;

DOI:10.1021/jo01326a033

upstream raw materials:

N-phenyl-2-oxooxazolidine-3-sulfonamide

isopropylamine