1-Octadecanoyl-sn-glycero-3-phosphoethanolamine

Base Information

Chemical Name:1-Octadecanoyl-sn-glycero-3-phosphoethanolamine
CAS No.:69747-55-3
Molecular Formula:C23H48NO7P
Molecular Weight:481.60300
Hs Code.:
DSSTox Substance ID:DTXSID20914019
Nikkaji Number:J812.445K
Wikidata:Q27156597
Metabolomics Workbench ID:16374
Mol file:69747-55-3.mol

Synonyms:18:0 LYSO-PE;1-octadecanoyl-sn-glycero-3-phosphoethanolamine;LPE(18:0/0:0);PE(18:0/0:0);1-stearoyl-sn-glycero-3-phosphoethanolamine;69747-55-3;1-stearoyl-phosphatidylethenolamine;[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl] octadecanoate;[(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate;Octadecanoic acid, 3-[[(2-aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester, (R)-;Stearoyl lysophosphatidylethanolamine;LMGP02050001;SCHEMBL274812;LysoPE(18:0/0:0);CHEBI:83047;DTXSID20914019;Stearoyllysophophatidylethanolamine;Stearoyllysophosphatidylethanolamine;AKOS040740924;Lysophosphatidylethanolamine(18:0/0:0);1-stearoyl-sn-lysophosphatidylethanolamine;HY-103660;CS-0029589;C21484;Q27156597;1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine;(2-aminoethoxy)[2-hydroxy-3-(octadecanoyloxy)propoxy]phosphinic acid;(2R)-3-[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl octadecanoate;(2R)-3-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl octadecanoate;82T

Suppliers and Price of 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
1-Stearoyl-2-hydroxy-sn-glycero-3-PE
25mg
$ 179.00

Cayman Chemical
1-Stearoyl-2-hydroxy-sn-glycero-3-PE ≥95%
10 mg
$ 96.00

Cayman Chemical
1-Stearoyl-2-hydroxy-sn-glycero-3-PE ≥95%
5 mg
$ 60.00

American Custom Chemicals Corporation
1-STEAROYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 95.00%
5MG
$ 497.50

AK Scientific
[3-[2-Aminoethoxy(hydroxy)phosphoryl]oxy-2-hydroxypropyl]octadecanoate
25mg
$ 314.00

Total 10 raw suppliers

Chemical Property of 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine

Chemical Property:

PSA：138.12000
LogP:5.94460
XLogP3:3.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:25
Exact Mass:481.31683987
Heavy Atom Count:32
Complexity:479

Purity/Quality:

97% ^*data from raw suppliers

1-Stearoyl-2-hydroxy-sn-glycero-3-PE ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Lipids -> Unambiguous Lipids
Canonical SMILES:CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCN)O
Isomeric SMILES:CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCCN)O
Description 1-Stearoyl-2-hydroxy-sn-glycero-3-PE is a lysophospholipid. It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) receptor antagonist AM095 .
Uses Stearoyl Lysophophatidylethanolamine is used as a lipid biomarker for the diagnosis of cancer.

Technology Process of 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine

There total 2 articles about 1-Octadecanoyl-sn-glycero-3-phosphoethanolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96470-73-4
Octadecanoic acid (R)-3-[(2-amino-ethoxy)-hydroxy-phosphoryloxy]-2-benzyloxy-propyl ester

: 69747-55-3
LysoPE (18:0/0:0)

Guidance literature:: With hydrogen; palladium dihydroxide;

Reference yield:

: 85647-89-8
(S)-1-stearoyl-2-O-benzyl-sn-glycerol

: 69747-55-3
LysoPE (18:0/0:0)

Guidance literature:: Multi-step reaction with 2 steps

1: 1) POCl₃, 2) H₃O⁽¹⁺⁾

2: H₂ / Pd(OH)2

With oxonium; hydrogen; trichlorophosphate; palladium dihydroxide;

Reference yield:

: 69747-55-3
LysoPE (18:0/0:0)

: 720659-05-2
(9Z,11E)-(S)-13-(1-Methoxy-1-methyl-ethylperoxy)-octadeca-9,11-dienoic acid (R)-2-{hydroxy-[2-(trityl-amino)-ethoxy]-phosphoryloxy}-1-octadecanoyloxymethyl-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: N(Et)3

2: 1) Na₂CO₃, 2)dicyclohexylcarbodiimide, 4-dimethylaminopyridine

With dmap; sodium carbonate; triethylamine; dicyclohexyl-carbodiimide;