(1,4-Dimethoxynaphthalen-2-yl)acetic acid

Base Information

Chemical Name:(1,4-Dimethoxynaphthalen-2-yl)acetic acid
CAS No.:79971-33-8
Molecular Formula:C₁₄H₁₄O₄
Molecular Weight:246.263
Hs Code.:
NSC Number:157899
DSSTox Substance ID:DTXSID70303333
Wikidata:Q82048540

Synonyms:79971-33-8;2-(1,4-dimethoxynaphthalen-2-yl)acetic acid;(1,4-dimethoxynaphthalen-2-yl)acetic acid;NSC157899;DTXSID70303333;NSC-157899

Suppliers and Price of (1,4-Dimethoxynaphthalen-2-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (1,4-Dimethoxynaphthalen-2-yl)acetic acid

Chemical Property:

Vapor Pressure:1.61E-08mmHg at 25°C
Boiling Point:440.1°Cat760mmHg
Flash Point:168.9°C
Density:1.237g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:246.08920892
Heavy Atom Count:18
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C2=CC=CC=C21)OC)CC(=O)O

Technology Process of (1,4-Dimethoxynaphthalen-2-yl)acetic acid

There total 6 articles about (1,4-Dimethoxynaphthalen-2-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 79971-25-8
2-(cyanomethyl)-1,4-dimethoxynaphthalene

: 79971-33-8
2-(1,4-dimethoxynaphthalen-2-yl)acetic acid

Guidance literature:: With potassium hydroxide; In methanol; water; for 42h; Heating;
DOI:10.1021/jo00342a045

Reference yield: 79.0%

: 1619226-66-2
1,4-dimethoxy-2-(2-nitroethyl)naphthalene

: 79971-33-8
2-(1,4-dimethoxynaphthalen-2-yl)acetic acid

Guidance literature:: With acetic acid; dimethyl sulfoxide; sodium nitrite; at 35 ℃; for 2h;
DOI:10.1080/00397911.2014.905600

Reference yield:

: 10075-62-4
1,4-dimethoxynaphthalene

: 79971-33-8
2-(1,4-dimethoxynaphthalen-2-yl)acetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 93 percent / POCl₃ / 4 h / 80 °C

2: 94 percent / NaBH₄ / methanol / 20 °C

3: 96 percent / PBr₃ / CCl₄ / 0.5 h / 0 °C

4: 75 percent / ethanol / 3 h / Heating

5: 90 percent / NaOH / H₂O / 18 h / Heating

With sodium hydroxide; sodium tetrahydroborate; phosphorus tribromide; trichlorophosphate; In methanol; tetrachloromethane; ethanol; water; 1: Vilsmeier-Haak formylation;
DOI:10.1081/SCC-120015812