3-hydroxy-4,4-diMethyl-2-Pyrrolidinone

Base Information

• Chemical Name: 3-hydroxy-4,4-diMethyl-2-Pyrrolidinone
• CAS No.: 70006-38-1
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.159
• Mol file: 70006-38-1.mol

Synonyms:3-hydroxy-4,4-diMethyl-2-Pyrrolidinone;DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam;3-hydroxy-4,4-dimethyl-pyrrolidin-2-one;pantolactam;2-Pyrrolidinone,3-hydroxy-4,4-dimethyl;

Chemical Property of 3-hydroxy-4,4-diMethyl-2-Pyrrolidinone

Chemical Property:

• PSA: 52.82000
• LogP: -0.22080
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-hydroxy-4,4-dimethylpyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-hydroxy-4,4-diMethyl-2-Pyrrolidinone

There total 2 articles about 3-hydroxy-4,4-diMethyl-2-Pyrrolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide (4417-86-1) → DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam (70006-38-1) + pantolactone (79-50-5)

Guidance literature:

With ammonia; toluene-4-sulfonic acid; In methanol; at 250 ℃; for 4h; under 7220 - 11400 Torr; Heating;

DOI:10.1016/S0040-4020(03)00156-X

Reference yield:

pantolactone (79-50-5) → (R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide (4417-86-1) + DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam (70006-38-1)

Guidance literature:

With ammonia; toluene-4-sulfonic acid; In methanol; at 250 ℃; for 4h; under 7220 - 11400 Torr; Heating;

DOI:10.1016/S0040-4020(03)00156-X

Reference yield: 75.0%

DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam (70006-38-1) → 4,4-dimethylpyrrolidine-2,3-dione (1248826-72-3)

Guidance literature:

With sodium dichromate dihydrate; sulfuric acid; acetic acid; In water; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.tetasy.2010.06.028

upstream raw materials:

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide

pantolactone

Downstream raw materials:

4,4-dimethylpyrrolidine-2,3-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 70006-38-1 3-hydroxy-4,4-diMethyl-2-Pyrrolidinone

Send

Send

Metric Ton KG G Pound L ML

Send

Send