2-Naphthaleneacetaldehyde

Base Information

• Chemical Name: 2-Naphthaleneacetaldehyde
• CAS No.: 70080-13-6
• Molecular Formula: C12H10O
• Molecular Weight: 170.211
• DSSTox Substance ID: DTXSID00447592
• Nikkaji Number: J633.276E
• Wikidata: Q82266466
• Mol file: 70080-13-6.mol

Synonyms:2-Naphthaleneacetaldehyde;70080-13-6;2-naphthalen-2-ylacetaldehyde;2-(NAPHTHALEN-2-YL)ACETALDEHYDE;NAPHTHALEN-2-YLACETALDEHYDE;2-NAPHTHYLACETALDEHYDE;(2-Naphthyl)acetaldehyde;(naphthalen-2-yl)acetaldehyde;SCHEMBL720558;DTXSID00447592;ZONWDLKOOMKAKI-UHFFFAOYSA-N;MFCD02261775;AB11816;FT-0752624

Chemical Property of 2-Naphthaleneacetaldehyde

Chemical Property:

• PSA: 17.07000
• LogP: 2.58120
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 170.073164938
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

98%min ^*data from raw suppliers

Naphthalen-2-ylacetaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)CC=O

Technology Process of 2-Naphthaleneacetaldehyde

There total 2 articles about 2-Naphthaleneacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

(E)-3-(β-styryl)furan (114078-26-1) → 2-naphthylacetaldehyde (70080-13-6) + β-naphthaldehyde (66-99-9)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 40 ℃; for 3h; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1016/j.tet.2014.01.035

Reference yield:

2-naphthylethylene (827-54-3,28406-56-6) → 2-naphthylacetaldehyde (70080-13-6) + methyl 2-naphthyl ketone (93-08-3)

Guidance literature:

With water; palladium dichloride; In N,N-dimethyl-formamide; at 20 ℃; for 5h; Title compound not separated from byproducts;

DOI:10.1002/chem.200400644

Reference yield: 99.0%

2-[1,3]dithiolan-2-ylidene-1-phenyl-ethanone (5653-30-5) + 2-naphthylacetaldehyde (70080-13-6) → (E)-2-(1,3-dithiolan-2-ylidene)-4-(naphthalen-2-yl)-1-phenylbut-3-en-1-one

Guidance literature:

With methanol; aluminum (III) chloride; In acetonitrile; at 80 ℃; for 6h;

DOI:10.1021/jo5017234

upstream raw materials:

2-naphthylethylene

(E)-3-(β-styryl)furan

Downstream raw materials:

2-(naphthalen-2-yl)cyclohexan-1-one

C₂₆H₃₀N₄O₃

N-(4-cyanophenyl)-2-(naphthalen-2-yl)-2-oxoacetamide

N-(4-cyanophenyl)formamide

Refernces

• 1、 Wright, Joseph A.,Gaunt, Matthew J.,Spencer, Jonathan B.. "Novel anti-Markovnikov regioselectivity in the Wacker reaction of styrenes". . p. 949 - 955. Retrieved 2007/10/03.