3',5'-Bis(trifluoromethyl)propiophenone

Base Information

Chemical Name:3',5'-Bis(trifluoromethyl)propiophenone
CAS No.:85068-34-4
Molecular Formula:C11H8F6O
Molecular Weight:270.174
Hs Code.:2914700090
European Community (EC) Number:285-296-1
UNII:9CXA2S32LC
DSSTox Substance ID:DTXSID70234138
Nikkaji Number:J236.276G
Wikidata:Q72447397
Mol file:85068-34-4.mol

Synonyms:85068-34-4;3',5'-Bis(trifluoromethyl)propiophenone;1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-one;3,5-Bis(trifluoromethyl)propiophenone;1-[3,5-bis(trifluoromethyl)phenyl]propan-1-one;1-Propanone, 1-[3,5-bis(trifluoromethyl)phenyl]-;9CXA2S32LC;1-[3,5-Bis(trifluoromethyl)phenyl]-1-propanone;EINECS 285-296-1;MFCD00009911;3,5-difluoromethyl)phenylacetone;UNII-9CXA2S32LC;SCHEMBL5898589;VLRWCHKOSBUGMB-UHFFFAOYSA-;DTXSID70234138;C11-H8-F6-O;3',5'-Bistrifluoromethylpropiophenone;AKOS015852850;AC-11418;DS-15796;SY021817;CS-0152657;FT-0614479;1-[3,5-bis(trifluoromethyl)phenyl]-propan-1-one;A841189;1-[3,5-Bis(trifluoromethyl)phenyl]-1-propanone #;3 inverted exclamation mark ,5 inverted exclamation mark -Bis(trifluoromethyl)propiophenone

Suppliers and Price of 3',5'-Bis(trifluoromethyl)propiophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3'',5''-Bis(Trifluoromethyl)propiophenone
100mg
$ 60.00

SynQuest Laboratories
3',5'-Bis(trifluoromethyl)propiophenone 97%
25 g
$ 167.00

SynQuest Laboratories
3',5'-Bis(trifluoromethyl)propiophenone 97%
5 g
$ 37.00

Matrix Scientific
3',5'-Bis(trifluoromethyl)propiophenone 98%
1g
$ 10.00

Matrix Scientific
3',5'-Bis(trifluoromethyl)propiophenone 98%
5g
$ 49.00

Crysdot
1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-one 98%
25g
$ 127.00

American Custom Chemicals Corporation
3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE 95.00%
25G
$ 1182.12

American Custom Chemicals Corporation
3',5'-BIS(TRIFLUOROMETHYL)PROPIOPHENONE 95.00%
5G
$ 782.76

Ambeed
1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-one 98%
10g
$ 41.00

Ambeed
1-(3,5-Bis(trifluoromethyl)phenyl)propan-1-one 98%
1g
$ 8.00

Total 31 raw suppliers

Chemical Property of 3',5'-Bis(trifluoromethyl)propiophenone

Chemical Property:

Vapor Pressure:0.705mmHg at 25°C
Refractive Index:n20/D 1.4245(lit.)
Boiling Point:185.2 °C at 760 mmHg
Flash Point:76.1 °C
PSA：17.07000
Density:1.321 g/cm³
LogP:4.31690
Storage Temp.:2-8°C
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:270.04793385
Heavy Atom Count:18
Complexity:284

Purity/Quality:

97% ^*data from raw suppliers

3'',5''-Bis(Trifluoromethyl)propiophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Technology Process of 3',5'-Bis(trifluoromethyl)propiophenone

There total 2 articles about 3',5'-Bis(trifluoromethyl)propiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 401-95-6
3,5-Bis(trifluoromethyl)benzaldehyde

: 85068-34-4
1-[3,5-bis(trifluoromethyl)phenyl]-propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether

2: CrO₃; aq. H₂SO₄

With chromium(VI) oxide; sulfuric acid; In diethyl ether; 2: Jones oxidation;
DOI:10.1016/j.bmcl.2004.04.093

Reference yield:

: 184888-50-4,742097-70-7,575488-43-6
1-[3,5-bis(trifluoromethyl)phenyl]propan-1-ol

: 85068-34-4
1-[3,5-bis(trifluoromethyl)phenyl]-propan-1-one

Guidance literature:: With chromium(VI) oxide; sulfuric acid;
DOI:10.1016/j.bmcl.2004.04.093

Reference yield: 90.0%

: 82560-12-1
5-(tert-butyl)-1H-pyrazol-3-amine

: 85068-34-4
1-[3,5-bis(trifluoromethyl)phenyl]-propan-1-one

: 5-(3,5-bis(trifluoromethyl)phenyl)-2-(tert-butyl)pyrazolo[1,5-a]pyrimidine

Guidance literature:: With [2,2]bipyridinyl; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; copper diacetate; In 1,2-dichloro-benzene; at 120 ℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.1c01343