4-n-Octadecyloxybenzoic acid

Base Information

• Chemical Name: 4-n-Octadecyloxybenzoic acid
• CAS No.: 15872-50-1
• Molecular Formula: C25H42 O3
• Molecular Weight: 390.607
• Hs Code.: 2918990090
• Mol file: 15872-50-1.mol

Synonyms:Benzoicacid, p-(octadecyloxy)- (8CI); 4-(Octadecyloxy)benzoic acid;p-Octadecyloxybenzoic acid; p-n-Octadecyloxybenzoic acid

Chemical Property of 4-n-Octadecyloxybenzoic acid

Chemical Property:

• Boiling Point: 506.4°Cat760mmHg
• Flash Point: 158.9°C
• PSA: 46.53000
• Density: 0.96g/cm³
• LogP: 8.02510

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 4-n-Octadecyloxybenzoic acid

There total 20 articles about 4-n-Octadecyloxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethyl ester of 4-hexadecyloxybenzoic acid (62443-20-3) → 4-(octadecyloxy)benzoic acid (15872-50-1)

Guidance literature:

With water; potassium hydroxide; In ethanol; for 2h; Reflux;

DOI:10.1002/chem.200903210

Reference yield: 85.0%

4-(octadecyloxy)benzaldehyde (4105-95-7) → 4-(octadecyloxy)benzoic acid (15872-50-1)

Guidance literature:

With sodium chlorite; potassium dihydrogenphosphate; recorcinol; In water; tert-butyl alcohol; at 20 ℃; for 1h;

DOI:10.1039/c9tc06456g

Reference yield: 69.0%

methyl 4-(octadecyloxy)benzoate (40654-37-3) → 4-(octadecyloxy)benzoic acid (15872-50-1)

Guidance literature:

With sodium hydroxide; In methanol; Reflux; Inert atmosphere;

DOI:10.1021/acs.jmedchem.7b01468

upstream raw materials:

n-iodooctadecane

4-hydroxy-benzoic acid

1-Bromooctadecane

methyl 4-(octadecyloxy)benzoate

Downstream raw materials:

4-nitrophenyl-4'-octadecyloxybenzoate

4-<(4'-octadecyloxyphenyl)benzoate>aminophenyl

Refernces

• 1、 Kolokolov,Kulyasov,Magomadova,Shapieva, Kh. K.,Mikhailov,Dushenko,Panyushkin. "Synthesis and luminescent properties of coordination compounds of europium(III), gadolinium(III), and terbium(III) with para-alkyloxybenzoic acids". . p. 1209 - 1211. Retrieved 2016.
• 2、 Dwivedi, Durgesh J.,Thakor, Akshay,Desai, Vipul,Sharma, Vinay S.,Patel. "Synthesis, mesomorphic properties and biological evolution of calamitic-shaped chalcone-based LCs: effect of lateral and terminal group". . p. 16 - 32. Retrieved 2021/05/26.
• 3、 Alaasar, Mohamed,Cai, Xiaoqian,Eremin, Alexey,Kurachkina, Marharyta,Lehmann, Anne,Liu, Feng,Nagaraj, Mamatha,Poppe, Marco,Poppe, Silvio,Tamba, Maria-Gabriela,Tschierske, Carsten,Vij, Jagdish K.. "Controlling the formation of heliconical smectic phases by molecular design of achiral bent-core molecules". . p. 3316 - 3336. Retrieved 2020/03/23.