Ethyl 5,8-dimethoxyquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 5,8-dimethoxyquinoline-3-carboxylate
CAS No.:71083-24-4
Molecular Formula:C14H15NO4
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID10594304
Wikidata:Q82489100

Synonyms:ethyl 5,8-dimethoxyquinoline-3-carboxylate;71083-24-4;3-Quinolinecarboxylic acid, 5,8-dimethoxy-, ethyl ester;SCHEMBL7189373;DTXSID10594304;ODCXOKRBMHUWCT-UHFFFAOYSA-N

Suppliers and Price of Ethyl 5,8-dimethoxyquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 5,8-dimethoxyquinoline-3-carboxylate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:261.10010796
Heavy Atom Count:19
Complexity:310

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(C=CC(=C2N=C1)OC)OC

Technology Process of Ethyl 5,8-dimethoxyquinoline-3-carboxylate

There total 1 articles about Ethyl 5,8-dimethoxyquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.5%

: 89446-07-1
4-Chloro-5,8-dimethoxy-quinoline-3-carboxylic acid ethyl ester

: 71083-24-4
ethyl 5,8-dimethoxy-3-quinolinecarboxylate

: 89446-08-2
ethyl 1,2,3,4-tetrahydro-5,8-dimethoxy-3-quinolinecarboxylate

: 77156-82-2
5,8-Dimethoxy-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Guidance literature:: With hydrogen; triethylamine; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00128a040

Reference yield:

: 71083-24-4
ethyl 5,8-dimethoxy-3-quinolinecarboxylate

: 294174-10-0
7-ethyl-4-(2-nitrophenyl)pyrido[3,2-g]quinolinecarboxylate-5,10-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / cerium ammonium nitrate / acetonitrile; H₂O / 1 h / 20 °C

2: 10 percent / acetic anhydride / acetonitrile / 64 h / Heating

With ammonium cerium(IV) nitrate; acetic anhydride; In water; acetonitrile; 2: Diels-Alder reaction;
DOI:10.1021/jm0108496