Benzaldehyde, 2-iodo-3,5-dimethoxy-

Base Information

• Chemical Name: Benzaldehyde, 2-iodo-3,5-dimethoxy-
• CAS No.: 71202-01-2
• Molecular Formula: C9H9IO3
• Molecular Weight: 292.073
• DSSTox Substance ID: DTXSID20465915
• Nikkaji Number: J1.804.669E
• Wikidata: Q82292215
• Mol file: 71202-01-2.mol

Synonyms:2-Iodo-3,5-dimethoxybenzaldehyde;Benzaldehyde, 2-iodo-3,5-dimethoxy-;71202-01-2;DTXSID20465915;EN300-6488778;Z2311077303

Chemical Property of Benzaldehyde, 2-iodo-3,5-dimethoxy-

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 291.95964
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)OC)I)C=O

Technology Process of Benzaldehyde, 2-iodo-3,5-dimethoxy-

There total 6 articles about Benzaldehyde, 2-iodo-3,5-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3,5-dimethoxybenzaldehdye (7311-34-4) → 3,5-dimethoxy-2-iodobenzaldehyde (71202-01-2)

Guidance literature:

With iodine; silver trifluoroacetate; In dichloromethane; at 20 ℃; for 5h;

DOI:10.3762/bjoc.12.266

Reference yield:

3,5-dimethoxybenzoic acid (1132-21-4) → 3,5-dimethoxy-2-iodobenzaldehyde (71202-01-2)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂

2: H₂, quinoline, sulfur / Pd-BaSO₄ / xylene

3: I₂, HgO / benzene

With quinoline; thionyl chloride; hydrogen; iodine; sulfur; mercury(II) oxide; palladium on barium sulfate; In xylene; benzene;

Reference yield:

3,5-dimethoxybenzoyl chloride (17213-57-9) → 3,5-dimethoxy-2-iodobenzaldehyde (71202-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂, quinoline, sulfur / Pd-BaSO₄ / xylene

2: I₂, HgO / benzene

With quinoline; hydrogen; iodine; sulfur; mercury(II) oxide; palladium on barium sulfate; In xylene; benzene;

upstream raw materials:

3,5-dimethoxybenzaldehdye

3,5-dimethoxybenzoic acid

3,5-dimethoxybenzoyl chloride

3,5-Dihydroxybenzoic acid