4-Propanamidobenzene-1-sulfonyl chloride

Base Information

• Chemical Name: 4-Propanamidobenzene-1-sulfonyl chloride
• CAS No.: 7139-88-0
• Molecular Formula: C9H10ClNO3S
• Molecular Weight: 247.702
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID40512556
• Wikidata: Q82371866
• Mol file: 7139-88-0.mol

Synonyms:7139-88-0;4-(PROPIONYLAMINO)BENZENESULFONYL CHLORIDE;4-propanamidobenzene-1-sulfonyl chloride;4-(propanoylamino)benzenesulfonyl chloride;Benzenesulfonyl chloride, 4-[(1-oxopropyl)amino]-;SCHEMBL1102000;DTXSID40512556;MFCD08457411;AKOS000150448;4-Propionamidobenzene-1-sulfonylchloride;4-Propionamidobenzene-1-sulfonyl chloride;BS-36379;CS-0252489;EN300-60505

Chemical Property of 4-Propanamidobenzene-1-sulfonyl chloride

Chemical Property:

• PSA: 71.62000
• LogP: 3.11640
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 247.0069920
• Heavy Atom Count: 15
• Complexity: 315

Purity/Quality:

95% ^*data from raw suppliers

MC002435:4-Propionylamino-benzenesulfonylchloride 97 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)NC1=CC=C(C=C1)S(=O)(=O)Cl

Technology Process of 4-Propanamidobenzene-1-sulfonyl chloride

There total 2 articles about 4-Propanamidobenzene-1-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(phenyl)-2-methylacetamide (620-71-3) → N-propionyl-sulfanilyl chloride (7139-88-0)

Guidance literature:

With chlorosulphuric acid;

DOI:10.1021/ja01865a052 DOI:10.1021/ja01878a022

Reference yield:

→ N-propionyl-sulfanilyl chloride (7139-88-0)

Guidance literature:

N-Propionyl-anilin, Chlorsulfonsaeure;

Reference yield: 98.2%

4-methoxypyrimidin-2-amine (155-90-8) + N-propionyl-sulfanilyl chloride (7139-88-0) → C14H16N4O4S

Guidance literature:

With pyridine; calcium chloride; at 75 ℃; for 5h; Temperature; Reagent/catalyst;

upstream raw materials:

N-(phenyl)-2-methylacetamide

Downstream raw materials:

(N-propionyl-sulfanilyl)-guanidine

N-propionyl-sulfanilic acid amide

N-propionyl-sulfanilic acid hydrazide

sulfanilic acid-(4-dimethylamino-anilide)