2-(chloromethyl)-1,3-dimethoxyBenzene

Base Information

Chemical Name:2-(chloromethyl)-1,3-dimethoxyBenzene
CAS No.:71819-90-4
Molecular Formula:C9H11ClO2
Molecular Weight:186.638
Hs Code.:
DSSTox Substance ID:DTXSID40507528
Wikidata:Q82363798

Synonyms:71819-90-4;2-(chloromethyl)-1,3-dimethoxyBenzene;Benzene, 2-(chloromethyl)-1,3-dimethoxy-;2,6-dimethoxybenzyl chloride;SCHEMBL1291912;DTXSID40507528;WORNMIRYYMSPOY-UHFFFAOYSA-N;FT-0741586

Suppliers and Price of 2-(chloromethyl)-1,3-dimethoxyBenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-(chloromethyl)-1,3-dimethoxyBenzene

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:186.0447573
Heavy Atom Count:12
Complexity:118

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=CC=C1)OC)CCl

Technology Process of 2-(chloromethyl)-1,3-dimethoxyBenzene

There total 5 articles about 2-(chloromethyl)-1,3-dimethoxyBenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 16700-55-3
2,6-dimethoxybenzyl alcohol

: 71819-90-4
2-(chloromethyl)-1,3-dimethoxybenzene

Guidance literature:: With pyridine; thionyl chloride; In chloroform; at 20 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1021/acs.orglett.0c01226

Reference yield:

: 2065-27-2
methyl 2,6-dimethoxybenzoate

: 71819-90-4
2-(chloromethyl)-1,3-dimethoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

2: thionyl chloride; pyridine / chloroform / 0.17 h / 20 °C / Inert atmosphere

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran; chloroform;
DOI:10.1021/acs.orglett.0c01226