Valeric acid, 5-(p-aminophenoxy)-

Base Information

• Chemical Name: Valeric acid, 5-(p-aminophenoxy)-
• CAS No.: 103852-82-0
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.245
• DSSTox Substance ID: DTXSID80146112
• Wikidata: Q83010851
• Mol file: 103852-82-0.mol

Synonyms:103852-82-0;Valeric acid, 5-(p-aminophenoxy)-;5-(4-aminophenoxy)pentanoic acid;5-(p-Aminophenoxy)valeric acid;M & B 2966;BRN 3531123;4-13-00-01031 (Beilstein Handbook Reference);Pentanoic acid,5-(4-aminophenoxy)-;starbld0026794;SCHEMBL16245586;DTXSID80146112;AKOS040754329;LS-161051

Chemical Property of Valeric acid, 5-(p-aminophenoxy)-

Chemical Property:

• Vapor Pressure: 4.33E-08mmHg at 25°C
• Boiling Point: 428.1°Cat760mmHg
• Flash Point: 212.7°C
• PSA: 72.55000
• Density: 1.186g/cm³
• LogP: 2.48370
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 209.10519334
• Heavy Atom Count: 15
• Complexity: 188

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1N)OCCCCC(=O)O

Technology Process of Valeric acid, 5-(p-aminophenoxy)-

There total 7 articles about Valeric acid, 5-(p-aminophenoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(4-nitrophenoxy)pentanenitrile (104296-36-8) → 5-(4-amino-phenoxy)-valeric acid (103852-82-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; aqueous hydrochloric acid

2: Hydrogenation

With hydrogenchloride; acetic acid;

Reference yield:

1-(4-bromobutoxy)-4-nitrobenzene (55502-03-9) → 5-(4-amino-phenoxy)-valeric acid (103852-82-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium cyanide; aqueous ethanol

2: aq.-ethanolic NaOH-solution

3: Hydrogenation

With potassium cyanide; sodium hydroxide; ethanol;

Reference yield:

acetic acid-[4-(4-cyano-butoxy)-anilide] (857949-35-0) → 5-(4-amino-phenoxy)-valeric acid (103852-82-0)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

5-(4-nitrophenoxy)pentanoic acid

acetic acid-[4-(4-cyano-butoxy)-anilide]

1-(4-bromobutoxy)-4-nitrobenzene

4-(4-nitrophenoxy)butanoic acid