Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

2-(Trifluoromethyl)benzyl chloride

Base Information Edit
  • Chemical Name:2-(Trifluoromethyl)benzyl chloride
  • CAS No.:21742-00-7
  • Molecular Formula:C8H6ClF3
  • Molecular Weight:194.584
  • Hs Code.:29039990
  • European Community (EC) Number:244-560-6
  • DSSTox Substance ID:DTXSID20176135
  • Nikkaji Number:J225.428J
  • Wikidata:Q72511784
  • Mol file:21742-00-7.mol
2-(Trifluoromethyl)benzyl chloride

Synonyms:2-(Trifluoromethyl)benzyl chloride;21742-00-7;1-(Chloromethyl)-2-(trifluoromethyl)benzene;2-(trifluoromethyl)benzylchloride;2-trifluoromethylbenzyl chloride;o-trifluoromethylbenzyl chloride;Benzene, 1-(chloromethyl)-2-(trifluoromethyl)-;EINECS 244-560-6;2-trifluoromethylbenzylchloride;SCHEMBL121915;2-(Chloromethyl)benzotrifluoride;DTXSID20176135;o-(Trifluoromethyl)Benzyl Chloride;a'-Chloro-a,a,a-trifluoro-o-xylene;CK2026;MFCD00009920;STK503679;AKOS000262076;AC-9762;AM62178;1-chloromethyl-2-trifluoromethyl-benzene;2-(Trifluoromethyl)benzyl chloride, 97%;PS-10659;FT-0608758;T2731;1-(chloromethyl)-2-(trifluoromethyl)-benzene;EN300-09854;A22552;J-506669;alpha-Chloro-alpha',alpha',alpha'-trifluoro-o-xlylene;Z56347086;1-(chloromethyl)-2-(trifluoromethyl)benzene

Suppliers and Price of 2-(Trifluoromethyl)benzyl chloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • 2-Trifluoromethylbenzyl Chloride|
  • 5g
  • $ 418.00
  • TRC
  • 2-(Trifluoromethyl)benzyl Chloride
  • 50g
  • $ 1055.00
  • TRC
  • 2-(Trifluoromethyl)benzyl Chloride
  • 5g
  • $ 130.00
  • TCI Chemical
  • 2-(Trifluoromethyl)benzyl Chloride >98.0%(GC)
  • 5g
  • $ 55.00
  • TCI Chemical
  • 2-(Trifluoromethyl)benzyl Chloride >98.0%(GC)
  • 25g
  • $ 178.00
  • SynQuest Laboratories
  • 2-(Trifluoromethyl)benzyl Chloride 97%
  • 100 g
  • $ 255.00
  • SynQuest Laboratories
  • 2-(Trifluoromethyl)benzyl Chloride 97%
  • 5 g
  • $ 25.00
  • SynQuest Laboratories
  • 2-(Trifluoromethyl)benzyl Chloride 97%
  • 25 g
  • $ 85.00
  • Sigma-Aldrich
  • 2-(Trifluoromethyl)benzyl chloride 97%
  • 5g
  • $ 61.40
  • Sigma-Aldrich
  • 2-(Trifluoromethyl)benzyl chloride 97%
  • 25g
  • $ 180.00
Total 82 raw suppliers
Chemical Property of 2-(Trifluoromethyl)benzyl chloride Edit
Chemical Property:
  • Appearance/Colour:Clear light yellow liquid 
  • Vapor Pressure:7.78E-08mmHg at 25°C 
  • Refractive Index:n20/D 1.469(lit.)  
  • Boiling Point:177.4 °C at 760 mmHg 
  • Flash Point:70 °C 
  • PSA:0.00000 
  • Density:1.291 g/cm3 
  • LogP:3.44420 
  • Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C 
  • Sensitive.:Lachrymatory 
  • XLogP3:3.2
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:194.0110124
  • Heavy Atom Count:12
  • Complexity:144
Purity/Quality:

99% *data from raw suppliers

2-Trifluoromethylbenzyl Chloride| *data from reagent suppliers

Safty Information:
  • Pictogram(s): Corrosive
  • Hazard Codes:
  • Statements: 34-36/37 
  • Safety Statements: 23-26-27-36/37/39-45 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1=CC=C(C(=C1)CCl)C(F)(F)F
  • Uses 2-(Trifluoromethyl)benzyl chloride is used in preparation of phenyl-substituted carboxylic acid derivatives as PAI-1 inhibitors. 2-(Trifluoromethyl)benzyl chloride reacts with 2-benzo[b]thienyllithium to yield 6-fluorobenzo[b]naphtho[2,3-d]thiophene.
Technology Process of 2-(Trifluoromethyl)benzyl chloride

There total 4 articles about 2-(Trifluoromethyl)benzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With thionyl chloride; at 10 - 65 ℃; under 675.068 Torr; Temperature; Concentration;
Guidance literature:
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / water / 1.33 h / 0 - 10 °C
2: thionyl chloride / 10 - 65 °C / 675.07 Torr
With sodium tetrahydroborate; thionyl chloride; In water;
Guidance literature:
Multistep reaction; (i) LiAlH4, (ii) SOCl2;
DOI:10.1021/jm00299a007
Post RFQ for Price