Piperazine, 1-[2-(phenylthio)ethyl]-

Base Information

Chemical Name:Piperazine, 1-[2-(phenylthio)ethyl]-
CAS No.:73446-34-1
Molecular Formula:C12H18N2S
Molecular Weight:222.35000
Hs Code.:
DSSTox Substance ID:DTXSID80357206
Wikidata:Q82137011

Synonyms:73446-34-1;1-[2-(PHENYLSULFANYL)ETHYL]PIPERAZINE;Piperazine, 1-[2-(phenylthio)ethyl]-;Oprea1_364038;Oprea1_812646;SCHEMBL11375264;DTXSID80357206;AKOS000506842;EN300-58012;AB01001876-01

Suppliers and Price of Piperazine, 1-[2-(phenylthio)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Piperazine, 1-[2-(phenylthio)ethyl]-

Chemical Property:

Boiling Point:140-141 °C(Press: 0.50 Torr)
PSA：40.57000
Density:1.12±0.1 g/cm3(Predicted)
LogP:1.95060
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:222.11906976
Heavy Atom Count:15
Complexity:163

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CCSC2=CC=CC=C2

Technology Process of Piperazine, 1-[2-(phenylthio)ethyl]-

There total 3 articles about Piperazine, 1-[2-(phenylthio)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 59264-54-9
1-ethoxycarbonyl-4-(2-phenylthioethyl)piperazine hydrochloride

: 73446-34-1
1-(2-phenylthioethyl)piperazine

Guidance literature:: With potassium hydroxide; In ethanol;
DOI:10.1135/cccc19832395

Reference yield:

: 6308-85-6
1-(2-chloroethyl)-4-(ethoxycarbonyl)piperazine hydrochloride

: 73446-34-1
1-(2-phenylthioethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / K₂CO₃, HCl / acetone; diethyl ether

2: 85 percent / KOH / ethanol

With hydrogenchloride; potassium hydroxide; potassium carbonate; In diethyl ether; ethanol; acetone;
DOI:10.1135/cccc19832395

Reference yield:

: 108-98-5
thiophenol

: 73446-34-1
1-(2-phenylthioethyl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / K₂CO₃, HCl / acetone; diethyl ether

2: 85 percent / KOH / ethanol

With hydrogenchloride; potassium hydroxide; potassium carbonate; In diethyl ether; ethanol; acetone;
DOI:10.1135/cccc19832395