Chemical Property of Gardimycin
Chemical Property:
- Boiling Point:2194.7±65.0 °C(Predicted)
- PKA:2.74±0.70(Predicted)
- Density:1.42±0.1 g/cm3(Predicted)
- Solubility.:Soluble in ethanol;methanol;DMSO;dimethyl formamide
- XLogP3:-0.7
- Hydrogen Bond Donor Count:23
- Hydrogen Bond Acceptor Count:24
- Rotatable Bond Count:54
- Exact Mass:1752.97742054
- Heavy Atom Count:124
- Complexity:3700
- Purity/Quality:
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>98% by HPLC *data from raw suppliers
Actagardin *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CCC(C)C(C(=O)NC(CCC(=O)O)C(=O)NC(CC)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NCC(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CC)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)NC(C)C(=O)NC(C)C(=O)O)NC(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)C(C)N
- Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](CC)C(=O)N[C@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](C)C(=O)NCC(=O)N[C@H](CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)O)NC(=O)[C@@H](CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)N
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Uses
Actagardin is a high molecular weight tetracyclic antibiotic produced by several species of Actinoplanes. Actagardin is a lantibiotic in which the macrocyclic rings are formed by thioether, rather than disulphide, bridges. Actagardin is a potent Gram positive and Gram negative antibiotic. Actagardin acts by inhibition of peptidoglycan biosynthesis.
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Therapeutic Function
Antibiotic
