N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide

Base Information

Chemical Name:N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide
CAS No.:738546-03-7
Molecular Formula:C14H21N3O
Molecular Weight:247.34
Hs Code.:
DSSTox Substance ID:DTXSID50388926
Wikidata:Q82184184

Synonyms:N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide;738546-03-7;N-(4-aminophenyl)-3-piperidin-1-ylpropanamide;1-Piperidinepropanamide, N-(4-aminophenyl)-;SCHEMBL4750052;DTXSID50388926;AKOS000137958;FT-0753472;EN300-62314;N-(4-aminophenyl)-3-(1-piperidinyl)propanamide;Z240102432

Suppliers and Price of N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:247.168462302
Heavy Atom Count:18
Complexity:256

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)CCC(=O)NC2=CC=C(C=C2)N

Technology Process of N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide

There total 6 articles about N-(4-aminophenyl)-3-(piperidin-1-yl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 90279-43-9
N-(4-nitro-phenyl)-3-(piperidin-1-yl)-propionamide

: 738546-03-7
N-(4-amino-phenyl)-3-(piperidin-1-yl)-propionamide

Guidance literature:: With hydrogen; palladium over charcoal; In ethanol; under 760.051 Torr;

Reference yield:

: 19313-88-3
3-chloro-N-(4-nitrophenyl)propanamide

: 738546-03-7
N-(4-amino-phenyl)-3-(piperidin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / methanol / 0 - 20 °C

2: 92 percent / ammonium formate; Pd/C / dimethylformamide / 16 h / 20 °C

With palladium on activated charcoal; ammonium formate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/ja0661919

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 738546-03-7
N-(4-amino-phenyl)-3-(piperidin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / 16 h / 50 °C

2: 100 percent / methanol / 0 - 20 °C

3: 92 percent / ammonium formate; Pd/C / dimethylformamide / 16 h / 20 °C

With palladium on activated charcoal; ammonium formate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/ja0661919