1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-

Base Information

Chemical Name:1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-
CAS No.:741709-19-3
Molecular Formula:C16H12N2
Molecular Weight:232.285
Hs Code.:
DSSTox Substance ID:DTXSID10456958
Wikidata:Q82279605

Synonyms:741709-19-3;1-methyl-2-phenyl-1H-indole-5-carbonitrile;1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-;SCHEMBL11689499;DTXSID10456958

Suppliers and Price of 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:232.100048391
Heavy Atom Count:18
Complexity:336

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)C#N)C=C1C3=CC=CC=C3

Technology Process of 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl-

There total 5 articles about 1H-Indole-5-carbonitrile, 1-methyl-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 591-50-4
iodobenzene

: 91634-11-6
N-methyl-5-cyanoindole

: 741709-19-3
1-methyl-2-phenyl-1H-indole-5-carbonitrile

Guidance literature:: With silver(I) acetate; palladium diacetate; acetic acid; for 4h; regioselective reaction; Sealed tube; Milling;
DOI:10.1021/acs.joc.9b01280

Reference yield: 65.0%

: 91634-11-6
N-methyl-5-cyanoindole

: 98-80-6
phenylboronic acid

: 741709-19-3
1-methyl-2-phenyl-1H-indole-5-carbonitrile

Guidance literature:: With dipotassium peroxodisulfate; sulfuric acid; In methanol; at 20 ℃; for 10h;
DOI:10.1039/c4cy00040d

Reference yield: 40.0%

: diphenyliodonium tetrafluoroborate

: 91634-11-6
N-methyl-5-cyanoindole

: 741709-19-3
1-methyl-2-phenyl-1H-indole-5-carbonitrile

Guidance literature:: With palladium containing [Zr₆O₄(OH)₄(terephthalate)_4.75(1,2,4,5-benzenetetracarboxylate)_1.25]; at 80 ℃; for 24h;
DOI:10.1002/cssc.202000378