(H-CYS-PHE-OH)2

Base Information

• Chemical Name: (H-CYS-PHE-OH)2
• CAS No.: 62130-80-7
• Molecular Formula: C₂₄H₃₀N₄O₆S₂
• Molecular Weight: 534.657
• Mol file: 62130-80-7.mol

Synonyms:NSC333713

Chemical Property of (H-CYS-PHE-OH)2

Chemical Property:

• Vapor Pressure: 1.28E-31mmHg at 25°C
• Boiling Point: 861.2 °C at 760 mmHg
• Flash Point: 474.6 °C
• PSA: 235.44000
• Density: 1.385 g/cm³
• LogP: 2.82900
• Storage Temp.: -15°C

Purity/Quality:

99% ^*data from raw suppliers

(H-Cys-Phe-OH)2 (Disulfide bond) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (H-CYS-PHE-OH)2

There total 2 articles about (H-CYS-PHE-OH)2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-[N,N'-bis-(4-nitro-benzyloxycarbonyl)-L-cystyl]-bis-L-phenylalanine (120176-51-4) → N,N'-L-cystyl-bis-L-phenylalanine (62130-80-7)

Guidance literature:

With palladium on activated charcoal; ethanol; Hydrogenation;

DOI:10.1017/S1092852900008580

Reference yield:

N,N'-[N,N'-bis-(4-nitro-benzyloxycarbonyl)-L-cystyl]-bis-L-phenylalanine diethyl ester (120640-19-9) → N,N'-L-cystyl-bis-L-phenylalanine (62130-80-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dioxane; aqueous NaOH

2: palladium/charcoal; aqueous ethanol / Hydrogenation

With 1,4-dioxane; sodium hydroxide; palladium on activated charcoal; ethanol;

DOI:10.1017/S1092852900008580

Reference yield:

N,N'-L-cystyl-bis-L-phenylalanine (62130-80-7) → H-Cys-Phe-OH (72704-23-5)

Guidance literature:

With sodium hydroxide; palladium on activated charcoal; Hydrogenation;

DOI:10.1017/S1092852900008580

upstream raw materials:

N,N'-[N,N'-bis-(4-nitro-benzyloxycarbonyl)-L-cystyl]-bis-L-phenylalanine

N,N'-[N,N'-bis-(4-nitro-benzyloxycarbonyl)-L-cystyl]-bis-L-phenylalanine diethyl ester

Downstream raw materials:

H-Cys-Phe-OH