1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI)

Base Information

Chemical Name:1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI)
CAS No.:744209-00-5
Molecular Formula:C13H11NO2
Molecular Weight:213.236
Hs Code.:
Mol file:744209-00-5.mol

Synonyms:BML-236;(E)-1-(3,5-dihydroxyphenyl)-2-(4-pyridyl)ethene;5-((E)-2-Pyridin-4-yl-vinyl)-benzene-1,3-diol;

Suppliers and Price of 1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-[(1E)-2-(4-PYRIDINYL)ETHENYL]-1,3-BENZENEDIOL 95.00%
5MG
$ 499.03

Total 2 raw suppliers

Chemical Property of 1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI)

Chemical Property:

PSA：53.35000
LogP:2.66320

Purity/Quality:

97-99% ^*data from raw suppliers

5-[(1E)-2-(4-PYRIDINYL)ETHENYL]-1,3-BENZENEDIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI)

There total 7 articles about 1,3-Benzenediol, 5-[(1E)-2-(4-pyridinyl)ethenyl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 223386-36-5
(E)-1-(3,5-dimethoxyphenyl)-2-(4-pyridyl)ethene

: 744209-00-5
(E)-5-[2(pyridin-4-yl)vinyl]benzene-1,3-diol

Guidance literature:: With boron tribromide; In dichloromethane; at -20 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2012.09.105

Reference yield:

: 705-76-0
3,5-dimethoxybenzyl alcohol

: 744209-00-5
(E)-5-[2(pyridin-4-yl)vinyl]benzene-1,3-diol

Guidance literature:: Multi-step reaction with 4 steps

1: 94.4 percent / SOCl₂ / diethyl ether / 3 h / 20 °C

2: 4 h / Heating

3: 68.5 percent / NaOEt / dimethylformamide; ethanol / 3 h / 20 °C

4: 78.5 percent / BBr₃ / CH₂Cl₂ / -10 - 0 °C

With thionyl chloride; sodium ethanolate; boron tribromide; In diethyl ether; ethanol; dichloromethane; N,N-dimethyl-formamide; 2: Wittig-Horner reaction;
DOI:10.1248/cpb.53.1587

Reference yield:

: 108957-75-1
diethyl 3,5-dimethoxybenzylphosphonate

: 744209-00-5
(E)-5-[2(pyridin-4-yl)vinyl]benzene-1,3-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 68.5 percent / NaOEt / dimethylformamide; ethanol / 3 h / 20 °C

2: 78.5 percent / BBr₃ / CH₂Cl₂ / -10 - 0 °C

With sodium ethanolate; boron tribromide; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.53.1587