6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal

Base Information

• Chemical Name: 6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal
• CAS No.: 74510-19-3
• Molecular Formula: C14H15NO3
• Molecular Weight: 245.278
• European Community (EC) Number: 833-374-6
• DSSTox Substance ID: DTXSID20503346
• Wikidata: Q82357082

Synonyms:74510-19-3;6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal;6-(1,3-DIOXOISOINDOL-2-YL)HEXANAL;6-(1,3-dioxoisoindolin-2-yl)hexanal;6-phthalimidohexan-1-al;SCHEMBL5818475;AGIYKNXRSZKPGG-UHFFFAOYSA-;DTXSID20503346;AGIYKNXRSZKPGG-UHFFFAOYSA-N;1,3-Dihydro-1,3-dioxo-2H-isoindole-2-hexanal;EN300-6735603;6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanal;Z3300765997;InChI=1/C14H15NO3/c16-10-6-2-1-5-9-15-13(17)11-7-3-4-8-12(11)14(15)18/h3-4,7-8,10H,1-2,5-6,9H2

Chemical Property of 6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 245.10519334
• Heavy Atom Count: 18
• Complexity: 316

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)CCCCCC=O

Technology Process of 6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal

There total 1 articles about 6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) → 6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal (74510-19-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / 0.25 h / 150 - 160 °C

2: 62.1 percent / pyridinium chlorochromate / CH₂Cl₂ / 2 h

With pyridinium chlorochromate; In dichloromethane;

DOI:10.1016/S0040-4020(01)89771-4

Reference yield: 75.0%

6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal (74510-19-3) + Phenyl vinyl ketone (768-03-6,26742-84-7) → 1-Phenyl-9-phthalimido-1,4-nonandion (74510-05-7)

Guidance literature:

With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; triethylamine; In ethanol; at 80 ℃; for 16h;

Reference yield: 74.0%

6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanal (74510-19-3) + benzalacetophenone (94-41-7) → 1,3-Diphenyl-9-phthalimido-1,4-nonandion (74510-06-8)

Guidance literature:

With 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride; triethylamine; In ethanol; at 80 ℃; for 16h;

upstream raw materials:

phthalic anhydride

Downstream raw materials:

[1-Benzyloxycarbonylamino-6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-hexyl]-phosphonic acid diphenyl ester

1,3-Diphenyl-9-phthalimido-1,4-nonandion

1-Phenyl-9-phthalimido-1,4-nonandion

C₂₃H₂₃NO₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 74510-19-3 2H-Isoindole-2-hexanal, 1,3-dihydro-1,3-dioxo-

Send

Send

Metric Ton KG G Pound L ML

Send

Send