3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide

Base Information

Chemical Name:3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide
CAS No.:746570-90-1
Molecular Formula:C13H19N3O2
Molecular Weight:249.313
Hs Code.:
DSSTox Substance ID:DTXSID40588615
Wikidata:Q82481393
Mol file:746570-90-1.mol

Synonyms:746570-90-1;3-amino-N-(2-morpholinoethyl)benzamide;3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide;3-amino-N-(2-morpholin-4-ylethyl)benzamide;Benzamide, 3-amino-N-[2-(4-morpholinyl)ethyl]-;SCHEMBL4572822;DTXSID40588615;MZBSDNLQCYWGGQ-UHFFFAOYSA-N;BBL031432;STL311148;AKOS000151064;MCULE-4802155492;DA-24159;3-amino-N-(2-morpholin-4-yl-ethyl)-benzamide

Suppliers and Price of 3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide

Chemical Property:

PSA：71.08000
LogP:1.42470
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:249.147726857
Heavy Atom Count:18
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CCNC(=O)C2=CC(=CC=C2)N

Technology Process of 3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide

There total 4 articles about 3-amino-N-[2-(morpholin-4-yl)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.6%

: 331845-86-4
N-(2-morpholinoethyl)-3-nitrobenzamide

: 746570-90-1
3-amino-N-(2-morpholinoethyl)benzamide

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; at 20 ℃; under 760.051 Torr; Inert atmosphere;
DOI:10.1021/jm301419d

Reference yield:

: 121-92-6
3-nitrobenzoic acid

: 746570-90-1
3-amino-N-(2-morpholinoethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / methanol / 20 °C / 760.05 Torr / Inert atmosphere

With 5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm301419d

Reference yield:

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 746570-90-1
3-amino-N-(2-morpholinoethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / methanol / 20 °C / 760.05 Torr / Inert atmosphere

With 5%-palladium/activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm301419d