2-(3-Methoxyphenoxy)-1-nitrobenzene

Base Information

• Chemical Name: 2-(3-Methoxyphenoxy)-1-nitrobenzene
• CAS No.: 74683-29-7
• Molecular Formula: C13H11NO4
• Molecular Weight: 245.235
• DSSTox Substance ID: DTXSID40429418
• Wikidata: Q82242445
• Mol file: 74683-29-7.mol

Synonyms:2-(3-Methoxyphenoxy)-1-nitrobenzene;74683-29-7;1-(3-methoxyphenoxy)-2-nitrobenzene;3-(2-Nitrophenoxy)anisole;SCHEMBL1339905;DTXSID40429418;AULPIOKBSAXCAB-UHFFFAOYSA-N

Chemical Property of 2-(3-Methoxyphenoxy)-1-nitrobenzene

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 245.06880783
• Heavy Atom Count: 18
• Complexity: 279

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC=C1)OC2=CC=CC=C2[N+](=O)[O-]

Technology Process of 2-(3-Methoxyphenoxy)-1-nitrobenzene

There total 5 articles about 2-(3-Methoxyphenoxy)-1-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

O-methylresorcine (150-19-6) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → 1-(3-methoxyphenoxy)-2-nitrobenzene (74683-29-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;

DOI:10.1021/ja504378p

Reference yield: 89.0%

O-methylresorcine (150-19-6) + 2-Chloronitrobenzene (88-73-3) → 1-(3-methoxyphenoxy)-2-nitrobenzene (74683-29-7)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 14h; Inert atmosphere;

DOI:10.1039/c8ob01701h

Reference yield: 77.0%

1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxybenzene (62790-77-6) + o-nitroiodobenzene (609-73-4) → 1-(3-methoxyphenoxy)-2-nitrobenzene (74683-29-7)

Guidance literature:

With oxygen; copper diacetate; caesium carbonate; In N,N-dimethyl-formamide; at 145 ℃; for 18h; under 760.051 Torr;

DOI:10.1039/c9nj01777a

upstream raw materials:

O-methylresorcine

2-nitrophenyl bromide

2-Chloronitrobenzene

2-methoxy-phenol

Downstream raw materials:

2-(3-methoxyphenoxy)aniline

3H-Phenoxazin-3-on

3-hydroxy-2'-nitrodiphenyl ether

3-(2-amino-phenoxy)-phenol