4-(2-Phenylethyl)furan-2(5H)-one

Base Information

Chemical Name:4-(2-Phenylethyl)furan-2(5H)-one
CAS No.:74796-66-0
Molecular Formula:C₁₂H₁₂O₂
Molecular Weight:188.226
Hs Code.:
DSSTox Substance ID:DTXSID70503558
Nikkaji Number:J2.952.532C
Wikidata:Q82357483

Synonyms:74796-66-0;4-(2-Phenylethyl)furan-2(5H)-one;DTXSID70503558

Suppliers and Price of 4-(2-Phenylethyl)furan-2(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2-Phenylethyl)furan-2(5H)-one

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:188.083729621
Heavy Atom Count:14
Complexity:237

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=CC(=O)O1)CCC2=CC=CC=C2

Technology Process of 4-(2-Phenylethyl)furan-2(5H)-one

There total 4 articles about 4-(2-Phenylethyl)furan-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 4-phenethyl-5-(toluene-4-sulfinyl)-dihydro-furan-2-one

: 74796-66-0
4-(2-phenylethyl)-5H-furan-2-one

Guidance literature:: With pyridine; for 12h; Reflux;
DOI:10.1055/s-0030-1259987

Reference yield:

: (E)-4-Methyl-2-oxo-6-phenyl-hex-3-enenitrile

: 74796-66-0
4-(2-phenylethyl)-5H-furan-2-one

: 74796-67-1
5-Benzyl-4-methyl-5H-furan-2-one

Guidance literature:: With dipyridinium dichromate; In N,N-dimethyl-formamide; at 25 ℃; for 12h; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(00)71458-4

Reference yield:

: 107647-42-7
trans-3-Methyl-5-phenyl-2-pentenal

: 74796-66-0
4-(2-phenylethyl)-5H-furan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: potassium cyanide/18-crown-6 complex / CH₂Cl₂ / 0.25 h / 0 °C

2: pyridinium dichromate / dimethylformamide / 12 h / 25 °C

3: pyridinium dichromate / dimethylformamide / 12 h / 25 °C

With potassium cyanide; dipyridinium dichromate; 18-crown-6 ether; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)71458-4