2-Fluoroglutaric acid

Base Information

Chemical Name:2-Fluoroglutaric acid
CAS No.:1578-67-2
Molecular Formula:C₅H₇FO₄
Molecular Weight:150.107
Hs Code.:2917190090
NSC Number:84358
DSSTox Substance ID:DTXSID00936370
Nikkaji Number:J40.597C
Mol file:1578-67-2.mol

Synonyms:2-Fluoroglutaric acid;2-fluoropentanedioic acid;1578-67-2;Glutaric acid, 2-fluoro-;Pentanedioic acid, 2-fluoro-;NSC 84358;BRN 1907747;AI3-28557;fluoroglutaric acid;WLN: QVYF2VQ;2-fluoranylpentanedioic acid;SCHEMBL2801076;DTXSID00936370;NSC84358;CCG-40485;NSC-84358;AKOS040812956;A810175;F2147-5786

Suppliers and Price of 2-Fluoroglutaric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 2-Fluoroglutaric acid

Chemical Property:

Vapor Pressure:0.000102mmHg at 25°C
Boiling Point:314.3°Cat760mmHg
Flash Point:143.9°C
PSA：74.60000
Density:1.414g/cm³
LogP:0.27390
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:150.03283686
Heavy Atom Count:10
Complexity:145

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)O)C(C(=O)O)F

Technology Process of 2-Fluoroglutaric acid

There total 11 articles about 2-Fluoroglutaric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90609-42-0
ethyl α-nitroglutarate

: 1578-67-2
2-Fluor-glutarsaeure

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) KF, 2.) FClO₃ / 1.) MeOH, RT, 0.5 h, 2.) THF, 0 deg C, 1 h

2: AIBN, n-Bu₃SnH / benzene / 2 h / Heating

3: 0.1 N NaOH / 3 h / Ambient temperature

With potassium fluoride; sodium hydroxide; perchloryl fluoride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene;
DOI:10.1021/jo00284a017

Reference yield:

: 110683-78-8
diethyl 2-fluoro-2-nitroglutarate

: 1578-67-2
2-Fluor-glutarsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: AIBN, n-Bu₃SnH / benzene / 2 h / Heating

2: 0.1 N NaOH / 3 h / Ambient temperature

With sodium hydroxide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene;
DOI:10.1021/jo00284a017