4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol

Base Information

Chemical Name:4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol
CAS No.:30165-97-0
Molecular Formula:C6H9N3O2S
Molecular Weight:187.222
Hs Code.:2934990002
European Community (EC) Number:608-450-5
UNII:9OQD3RT10O
DSSTox Substance ID:DTXSID10184249
Nikkaji Number:J2.438.871I
Wikidata:Q27272837
ChEMBL ID:CHEMBL1082515
Mol file:30165-97-0.mol

Synonyms:30165-97-0;4-morpholino-1,2,5-thiadiazol-3-ol;4-(morpholin-4-yl)-1,2,5-thiadiazol-3-ol;4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL;4-morpholin-4-yl-1,2,5-thiadiazol-3-one;1,2,5-Thiadiazol-3(2H)-one, 4-(4-morpholinyl)-;1,2,5-Thiadiazol-3-ol, 4-morpholino-;3-Morpholino-4-hydroxy-1,2,5-thiadiazole;UNII-9OQD3RT10O;9OQD3RT10O;3-Hydroxy-4-morpholino-1,2,5-thiazole;MFCD01820806;Timolol maleate specified impurity D [EP];3-hydroxy-4-morpholino-1,2,5-thiadiazole;4-Morpholino-1,2,5-thiadiazol-3-ol;Timolol EP Impurity D;ChemDiv2_002256;Oprea1_464928;3-Hydroxy-4-(morpholin-4-yl)-1,2,5-thiadiazole;MLS001002071;SCHEMBL1587527;CHEMBL1082515;DWUZILHYAJBUBR-UHFFFAOYSA-;DTXSID10184249;HMS1375G12;HMS2688N06;STK675866;AKOS001060909;AKOS005593909;PS-6157;4-Morpholino-1,2,5-thiadiazole-3-ol;SMR000368186;4-Morpholino-1,2,5-thiadiazol-3(2H)-one;AM20090409;CS-0187044;EU-0018774;FT-0650765;EN300-05872;4-(4-Morpholinyl)-1,2,5-thiadiazol-3-ol #;A20558;D97515;TIMOLOL MALEATE IMPURITY D [EP IMPURITY];SR-01000526363;J-515840;SR-01000526363-1;Q27272837;Z56928893;4-(morpholin-4-yl)-2,3-dihydro-1,2,5-thiadiazol-3-one;Timolol USP RC D;4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol;4-(4-Morpholinyl)-1,2,5-thiadiazol-3(2H)-one

Suppliers and Price of 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Hydroxy-4-morpholino-1,2,5-thiazole
2.5g
$ 1165.00

TRC
3-Hydroxy-4-morpholino-1,2,5-thiazole
250mg
$ 145.00

SynQuest Laboratories
3-Hydroxy-4-(morpholin-4-yl)-1,2,5-thiadiazole
1 g
$ 256.00

SynChem
4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-OL 95%
1 g
$ 270.00

Sigma-Aldrich
Timolol Related Compound D United States Pharmacopeia (USP) Reference Standard
20mg
$ 1160.00

Matrix Scientific
4-Morpholin-4-yl-1,2,5-thiadiazol-3-ol 97%
1g
$ 360.00

Crysdot
4-Morpholino-1,2,5-thiadiazol-3-ol 95+%
5g
$ 771.00

Chemenu
4-Morpholin-4-yl-1,2,5-thiadiazol-3-ol 95%
5g
$ 721.00

Atlantic Research Chemicals
4-Morpholin-4-yl-1,2,5-thiadiazol-3-ol 95%
1gm:
$ 137.85

Apolloscientific
4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol
1g
$ 160.00

Total 26 raw suppliers

Chemical Property of 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol

Chemical Property:

Vapor Pressure:5.7E-05mmHg at 25°C
Melting Point:200-204 °C
Refractive Index:1.753
Boiling Point:336.6 °C at 760 mmHg
PKA:6.20±0.40(Predicted)
Flash Point:157.3 °C
PSA：86.72000
Density:1.69 g/cm³
LogP:0.14530
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:187.04154771
Heavy Atom Count:12
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

3-Hydroxy-4-morpholino-1,2,5-thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NSNC2=O
Uses 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol. An intermediate for the preparation of Timolol

Technology Process of 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol

There total 5 articles about 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%