3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Base Information

Chemical Name:3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS No.:75530-94-8
Molecular Formula:C21H26N2O8
Molecular Weight:434.446
Hs Code.:
DSSTox Substance ID:DTXSID80392399
Nikkaji Number:J1.205.764D
Mol file:75530-94-8.mol

Synonyms:75530-94-8;4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester;3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;ST082969;DTXSID80392399;NUADIIYNSJFUSX-UHFFFAOYSA-N;AKOS024285295;FT-0672867;2-(Dimethoxymethyl)-4-(3-nitrophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid 3-methyl 5-isopropyl ester;4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 5-Isopropyl Ester 3-Methyl;5-ISOPROPYL 3-METHYL 2-(DIMETHOXYMETHYL)-6-METHYL-4-(3-NITROPHENYL)-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE

Suppliers and Price of 3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylicAcid5-IsopropylEster3-MethylEster
500mg
$ 970.00

American Custom Chemicals Corporation
4-(3-NITROPHENYL)-2-DIMETHOXYMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID-5-ISOPROPYL ESTER-3-METHYL ESTER 95.00%
500MG
$ 1593.90

Total 4 raw suppliers

Chemical Property of 3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Chemical Property:

PSA：128.91000
LogP:3.40520
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:9
Exact Mass:434.16891579
Heavy Atom Count:31
Complexity:764

Purity/Quality:

98%min ^*data from raw suppliers

4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylicAcid5-IsopropylEster3-MethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(C(=C(N1)C(OC)OC)C(=O)OC)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC(C)C
Uses 4-(3-Nitrophenyl)-2-dimethoxymethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 5-Isopropyl Ester 3-Methyl Ester (cas# 75530-94-8) is a compound useful in organic synthesis.

Technology Process of 3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

There total 4 articles about 3-O-methyl 5-O-propan-2-yl 2-(dimethoxymethyl)-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 40100-28-5
isopropyl 3-aminocrotonate

: 67448-15-1
(E,Z)-methyl 4,4-dimethoxy-2-(3-nitrobenzylidene)acetoacetate

: 75530-94-8
isopropyl 2-dimethoxymethyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate

Guidance literature:: In isopropyl alcohol; for 10h; Heating;
DOI:10.1007/PL00010185

Reference yield:

: 60705-25-1
4,4-dimethoxy-3-oxo-butyric acid methyl ester

: 75530-94-8
isopropyl 2-dimethoxymethyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / benzene / 5 h / Heating

2: 3 h / 100 - 120 °C

With piperidine; In benzene;
DOI:10.1016/S0040-4020(02)00542-2

Reference yield:

: 99-61-6
3-nitro-benzaldehyde

: 75530-94-8
isopropyl 2-dimethoxymethyl-3-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: piperidine / benzene / 5 h / Heating

2: 3 h / 100 - 120 °C

With piperidine; In benzene;
DOI:10.1016/S0040-4020(02)00542-2