4-Isopropylcyclohexanol

Base Information

• Chemical Name: 4-Isopropylcyclohexanol
• CAS No.: 15890-36-5
• Molecular Formula: C9H18 O
• Molecular Weight: 142.241
• Mol file: 15890-36-5.mol

Synonyms:Cyclohexanol,4-isopropyl-, trans- (8CI); trans-4-Isopropylcyclohexanol

Chemical Property of 4-Isopropylcyclohexanol

Chemical Property:

• Vapor Pressure: 0.068mmHg at 25°C
• Melting Point: 6°C(lit.)
• Refractive Index: 1.4640 to 1.4680
• Boiling Point: 203.125°C at 760 mmHg
• PKA: 15.30±0.40(Predicted)
• Flash Point: 80.796°C
• PSA: 20.23000
• Density: 0.914g/cm³
• LogP: 2.19350

Purity/Quality:

97% ^*data from raw suppliers

trans-4-Isopropylcyclohexanol >93.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Isopropylcyclohexanol

There total 25 articles about 4-Isopropylcyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

4-isopropyl-cyclohexanone (5432-85-9) → trans-4-isopropylcyclohexanol (15890-36-5) + cis 4-isopropylcyclohexanol (22900-08-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; tert-butyl methyl ether; at 7 - 20 ℃; for 1.25h;

Reference yield: 57.0%

toluene-4-sulfonic acid-(trans-4-isopropyl-cyclohexyl ester) (133231-34-2) → trans-4-isopropylcyclohexanol (15890-36-5)

Guidance literature:

With potassium hydroxide; In methanol; water; for 3h; Heating;

DOI:10.1021/jo951643d

Reference yield: 28.0%

4-isopropylcyclohexanol (4621-04-9) → 4-isopropyl-cyclohexanone (5432-85-9) + trans-4-isopropylcyclohexanol (15890-36-5)

Guidance literature:

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; dimethylsulfide; oxygen; copper(I) bromide dimethylsulfide complex; 6,6'-bis(C₈F₁₇(CH₂)4)-2,2'-bipyridine; In chlorobenzene; at 90 ℃; for 1.5h;

DOI:10.1016/S0040-4020(02)00250-8

upstream raw materials:

4-isopropyl-cyclohexanone

aluminum isopropoxide

4-Isopropylphenol

isopropyl alcohol

Downstream raw materials:

4-isopropylcyclohexyl mesylate

6-((cis-4-isopropylcyclohexyl)oxy)-2-methylquinoline

2-bromo-6-((cis-4-isopropylcyclohexyl)oxy)naphthalene

1-((6-((cis-4-isopropylcyclohexyl)oxy)naphthalen-2-yl)methyl)-4-(pyridin-2-yl)piperazine