1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione

Base Information

Chemical Name:1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione
CAS No.:75822-38-7
Molecular Formula:C16H10ClNO3
Molecular Weight:299.713
Hs Code.:
DSSTox Substance ID:DTXSID20367208
Nikkaji Number:J1.422.474B
Wikidata:Q82152895
ChEMBL ID:CHEMBL83686

Synonyms:1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione;75822-38-7;CBMicro_022733;Cambridge id 5528284;MLS001164390;CHEMBL83686;DTXSID20367208;HMS2826M08;CCG-9996;STL264101;AKOS009237325;SMR000496587;BIM-0022791.P001;AB00087476-01;1-(beta-Oxo-4-chlorophenethyl)-2,3-indolinedione;SR-01000211488;SR-01000211488-1

Suppliers and Price of 1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:299.0349209
Heavy Atom Count:21
Complexity:456

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)C(=O)N2CC(=O)C3=CC=C(C=C3)Cl

Technology Process of 1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione

There total 3 articles about 1-[2-(4-chlorophenyl)-2-oxoethyl]-1H-indole-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 937-20-2
p-chlorophenacyl chloride

: 75822-38-7
1-(4-chlorophenacyl)isatin

Guidance literature:: indole-2,3-dione; With sodium hydride; In N,N-dimethyl-formamide; for 0.25h;

With chloro-trimethyl-silane; In acetonitrile; at 50 ℃; for 1h;

p-chlorophenacyl chloride; In N,N-dimethyl-formamide; at 120 ℃; for 3h;
DOI:10.1007/BF02323373

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 536-38-9
4-chlorobenzoylmethyl bromide

: 75822-38-7
1-(4-chlorophenacyl)isatin

Guidance literature:: indole-2,3-dione; With polymeric BEMP; In acetonitrile; at 25 ℃; for 0.166667h;

4-chlorobenzoylmethyl bromide; In acetonitrile; at 45 ℃; for 16h;
DOI:10.1016/S0960-894X(00)00523-0