2-Amino-3-sulfanylpropanamide

Base Information

• Chemical Name: 2-Amino-3-sulfanylpropanamide
• CAS No.: 758-90-7
• Molecular Formula: C3H8N2OS
• Molecular Weight: 120.175
• DSSTox Substance ID: DTXSID30329413
• Mol file: 758-90-7.mol

Synonyms:2-amino-3-sulfanylpropanamide;Propanamide, 2-amino-3-mercapto-;758-90-7;cysteine aldimine;SCHEMBL469333;DTXSID30329413;AKOS006339913;EN300-156307

Chemical Property of 2-Amino-3-sulfanylpropanamide

Chemical Property:

• XLogP3: -1.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 120.03573406
• Heavy Atom Count: 7
• Complexity: 75.3

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)N)N)S

Technology Process of 2-Amino-3-sulfanylpropanamide

There total 1 articles about 2-Amino-3-sulfanylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dithiane-2,5-diol (40018-26-6) + sodium cyanide (773837-37-9) → rac-cysteine (921-01-7,3374-22-9,4371-52-2,40143-64-4,40143-66-6,40143-69-9,52-90-4) + cysteine amide (758-90-7) + C3H6N2S

Guidance literature:

With ammonium hydroxide; ammonium chloride; In water; for 6h;

DOI:10.1002/ejoc.202000089

Reference yield:

cysteine amide (758-90-7) + Ala-GALYR-Cys(Acm)-FG-NH2 → C46H71N15O11S2

Guidance literature:

cysteine amide; Ala-GALYR-Cys(Acm)-FG-NH₂; With guanidine hydrochloride; copper(II) sulfate; In aq. buffer; at 37 ℃; for 3h; under 760.051 Torr; pH=5 - 7;

With ethylenediaminetetraacetic acid; In aq. buffer; for 0.5h;

DOI:10.1039/d0ob01475c

upstream raw materials:

1,4-dithiane-2,5-diol

sodium cyanide