2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran

Base Information

Chemical Name:2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran
CAS No.:36518-04-4
Molecular Formula:C15H18O3
Molecular Weight:0
Hs Code.:
Mol file:36518-04-4.mol

Synonyms:(2S,5R)-5-Methyl-5-(4-methyl-furan-2-ylmethyl)-2,3,4,5-tetrahydro-[2,3']bifuranyl;

Suppliers and Price of 2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of 2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran

Chemical Property:

PSA：35.51000
LogP:4.03390

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran

There total 9 articles about 2,3,4,5-Tetrahydro-5-methyl-5-[(4-methyl-2-furanyl)methyl]-2,3'-bifuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127393-65-1,141505-71-7,132023-18-8
(2R)-2,6-Dimethyl-5-heptene-1,2-diol

: 36518-04-4
Athanasin

Guidance literature:: Multi-step reaction with 8 steps

1: 86 percent / 50percent aq. NaOH, p-toluenesulfonyl chloride / benzyltriethylammonium chloride (TEBA) / CH₂Cl₂ / 2 h / 0 deg C to r.t.

2: 1. n-butyllithium / 1. hexane, THF, r.t., 1 h; 2. THF, 0 deg C to r.t., 20 h

3: 88 percent / CH₂Cl₂ / 14 h / 0 deg C to r.t.

4: 1. OsO₄, N-methylmorpholine-N-oxide; 2. Na₂SO₃ / 1. t-butanol, diethyl ether, water, acetone, r.t., 3 d; 2. water, 30 min

5: 80 percent / Pb(OAc)4, CaCO₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

6: 1. n-butyllithium / 1. THF, hexane, -78 deg C, 1 h; 2. THF, -78 deg C, 20 h

7: 53 percent / citric acid / methanol; H₂O / 25 h / Ambient temperature

8: p-toluenesulfonyl chloride, pyridine / 20 h / Ambient temperature

With pyridine; lead(IV) acetate; sodium hydroxide; osmium(VIII) oxide; n-butyllithium; 4-methylmorpholine N-oxide; p-toluenesulfonyl chloride; citric acid; calcium carbonate; sodium sulfite; N-benzyl-N,N,N-triethylammonium chloride; In methanol; dichloromethane; water;
DOI:10.1016/S0040-4020(01)96205-2

Reference yield:

: 138944-68-0
(2S-trans)-2-(1,1-Dimethylethyl)-5-methyl-5-(4-methyl-3-pentenyl)-1,3-dioxolan-4-one

: 36518-04-4
Athanasin

Guidance literature:: Multi-step reaction with 9 steps

1: 93 percent / LiAlH₄ / diethyl ether / 20 h / -78 deg C to r.t.

2: 86 percent / 50percent aq. NaOH, p-toluenesulfonyl chloride / benzyltriethylammonium chloride (TEBA) / CH₂Cl₂ / 2 h / 0 deg C to r.t.

3: 1. n-butyllithium / 1. hexane, THF, r.t., 1 h; 2. THF, 0 deg C to r.t., 20 h

4: 88 percent / CH₂Cl₂ / 14 h / 0 deg C to r.t.

5: 1. OsO₄, N-methylmorpholine-N-oxide; 2. Na₂SO₃ / 1. t-butanol, diethyl ether, water, acetone, r.t., 3 d; 2. water, 30 min

6: 80 percent / Pb(OAc)4, CaCO₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

7: 1. n-butyllithium / 1. THF, hexane, -78 deg C, 1 h; 2. THF, -78 deg C, 20 h

8: 53 percent / citric acid / methanol; H₂O / 25 h / Ambient temperature

9: p-toluenesulfonyl chloride, pyridine / 20 h / Ambient temperature

With pyridine; lead(IV) acetate; sodium hydroxide; osmium(VIII) oxide; lithium aluminium tetrahydride; n-butyllithium; 4-methylmorpholine N-oxide; p-toluenesulfonyl chloride; citric acid; calcium carbonate; sodium sulfite; N-benzyl-N,N,N-triethylammonium chloride; In methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)96205-2

Reference yield:

: 138944-69-1
(2R)-2-methyl-2-(4-methylpent-3-en-1-yl)oxirane

: 36518-04-4
Athanasin

Guidance literature:: Multi-step reaction with 7 steps

1: 1. n-butyllithium / 1. hexane, THF, r.t., 1 h; 2. THF, 0 deg C to r.t., 20 h

2: 88 percent / CH₂Cl₂ / 14 h / 0 deg C to r.t.

3: 1. OsO₄, N-methylmorpholine-N-oxide; 2. Na₂SO₃ / 1. t-butanol, diethyl ether, water, acetone, r.t., 3 d; 2. water, 30 min

4: 80 percent / Pb(OAc)4, CaCO₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

5: 1. n-butyllithium / 1. THF, hexane, -78 deg C, 1 h; 2. THF, -78 deg C, 20 h

6: 53 percent / citric acid / methanol; H₂O / 25 h / Ambient temperature

7: p-toluenesulfonyl chloride, pyridine / 20 h / Ambient temperature

With pyridine; lead(IV) acetate; osmium(VIII) oxide; n-butyllithium; 4-methylmorpholine N-oxide; p-toluenesulfonyl chloride; citric acid; calcium carbonate; sodium sulfite; In methanol; dichloromethane; water;
DOI:10.1016/S0040-4020(01)96205-2