5,6-Dimethylpyrazine-2,3-diamine

Base Information

• Chemical Name: 5,6-Dimethylpyrazine-2,3-diamine
• CAS No.: 53114-83-3
• Molecular Formula: C₆H₁₀N₄
• Molecular Weight: 138.172
• Hs Code.: 2933990090
• NSC Number: 177408
• DSSTox Substance ID: DTXSID80306537
• Wikidata: Q82053680
• Mol file: 53114-83-3.mol

Synonyms:5,6-dimethylpyrazine-2,3-diamine;53114-83-3;5,6-DIMETHYL-PYRAZINE-2,3-DIAMINE;NSC177408;SCHEMBL11836648;DTXSID80306537;2,3-diamino-5,6-dimethylpyrazine;AKOS005206901;NSC-177408

Chemical Property of 5,6-Dimethylpyrazine-2,3-diamine

Chemical Property:

• Vapor Pressure: 0.000229mmHg at 25°C
• Boiling Point: 325.5°Cat760mmHg
• Flash Point: 176.8°C
• PSA: 77.82000
• Density: 1.222g/cm³
• LogP: 1.42020
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 138.090546336
• Heavy Atom Count: 10
• Complexity: 102

Purity/Quality:

99% ^*data from raw suppliers

5,6-DIMETHYL PYRAZINE-2,3-DIAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(N=C(C(=N1)N)N)C

Technology Process of 5,6-Dimethylpyrazine-2,3-diamine

There total 7 articles about 5,6-Dimethylpyrazine-2,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

5,6-dimethyl-[1,2,5]thiadiazolo[3,4-b]pyrazine (59503-57-0) → 5,6-dimethyl-pyrazine-2,3-diamine (53114-83-3)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In methanol; at 60 ℃; for 1h;

DOI:10.1039/a701579h

Reference yield:

3-chloro-5,6-dimethyl-pyrazin-2-ylamine (39213-71-3) → 5,6-dimethyl-pyrazine-2,3-diamine (53114-83-3)

Guidance literature:

With ammonia; water; copper;

DOI:10.1021/ja01122a017

Reference yield:

2-amino-3-bromo-5,6-dimethylpyrazine (6294-69-5) → 5,6-dimethyl-pyrazine-2,3-diamine (53114-83-3)

Guidance literature:

With ammonia; water; copper;

DOI:10.1021/ja01183a117

upstream raw materials:

3-chloro-5,6-dimethyl-pyrazin-2-ylamine

2-amino-3-bromo-5,6-dimethylpyrazine

5,6-dimethyl-[1,2,5]thiadiazolo[3,4-b]pyrazine

3-amino-5,6-dimethyl-1H-pyrazin-2-one

Downstream raw materials:

2,3-Dimethyl-1,4,5,8-tetraaza-naphthalin

2,3,6,7-Tetramethyl-1,4,5,8-tetra-azanaphthalin

2,3-bis-[(N-acetyl-sulfanilyl)-amino]-5,6-dimethyl-pyrazine

5,6-dimethyl-2-phenyl-1,2-dihydro-pyrazolo[3,4-b]pyrazin-3-one

Refernces