2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide

Base Information

Chemical Name:2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide
CAS No.:76492-00-7
Molecular Formula:C17H14N2O3
Molecular Weight:294.30500
Hs Code.:
DSSTox Substance ID:DTXSID20352230
Wikidata:Q82129258
ChEMBL ID:CHEMBL1383747
Mol file:76492-00-7.mol

Synonyms:76492-00-7;2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide;MLS001207365;SMR000513756;2H-Isoindole-2-acetamide, 1,3-dihydro-N-(2-methylphenyl)-1,3-dioxo-;2-(1,3-dioxoisoindol-2-yl)-N-(2-methylphenyl)acetamide;ST50052723;ChemDiv3_000565;Oprea1_211222;Oprea1_357943;CBDivE_012525;cid_721301;SCHEMBL9135817;CHEMBL1383747;BDBM69701;DTXSID20352230;HMS1474J15;HMS2815A15;N-(o-tolyl)-2-phthalimido-acetamide;STK069931;AKOS000631322;EU-0034853;SR-01000400354;SR-01000400354-1;BRD-K85411159-001-01-9;Z18271776;2-(1,3-dioxo-2-isoindolyl)-N-(2-methylphenyl)acetamide;2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(2-methylphenyl)acetamide;2-[1,3-bis(oxidanylidene)isoindol-2-yl]-N-(2-methylphenyl)ethanamide;2-(1,3-DIOXO-2,3-DIHYDRO-1H-ISOINDOL-2-YL)-N-(2-METHYLPHENYL)ACETAMIDE

Suppliers and Price of 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide

Chemical Property:

PSA：69.97000
LogP:2.81710
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:294.10044231
Heavy Atom Count:22
Complexity:453

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)CN2C(=O)C3=CC=CC=C3C2=O

Technology Process of 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide

There total 3 articles about 2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-N-o-tolyl-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1074-82-4
potassium phtalimide

: 37394-93-7
2-chloro-N-(2-methylphenyl)acetamide

: 76492-00-7
phthalimidoacet-o-toluidide

Guidance literature:: In N,N-dimethyl-formamide; for 4h; Heating;
DOI:10.1002/ardp.200300823

Reference yield:

: 95-53-4
o-toluidine

: 76492-00-7
phthalimidoacet-o-toluidide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / cooling

2: 68 percent / dimethylformamide / 4 h / Heating

In acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/ardp.200300823