4-Bromo-2,3,5,6-tetramethylphenol

Base Information

Chemical Name:4-Bromo-2,3,5,6-tetramethylphenol
CAS No.:17362-16-2
Molecular Formula:C10H13BrO
Molecular Weight:229.1136
Hs Code.:
NSC Number:128392
DSSTox Substance ID:DTXSID70299141
Wikidata:Q82041360

Synonyms:4-bromo-2,3,5,6-tetramethylphenol;17362-16-2;NSC128392;SCHEMBL205185;DTXSID70299141;IEDRBIMPVFYZOA-UHFFFAOYSA-N;NSC-128392

Suppliers and Price of 4-Bromo-2,3,5,6-tetramethylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Bromo-2,3,5,6-tetramethylphenol

Chemical Property:

Vapor Pressure:0.00066mmHg at 25°C
Boiling Point:299.7°Cat760mmHg
Flash Point:135°C
Density:1.354g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:228.01498
Heavy Atom Count:12
Complexity:144

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=C(C(=C1O)C)C)Br)C

Technology Process of 4-Bromo-2,3,5,6-tetramethylphenol

There total 8 articles about 4-Bromo-2,3,5,6-tetramethylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 3-phenyl-1-(2,3,5,6-tetramethylphenyl)propan-1-one

: 17362-16-2
4-bromo-2,3,5,6-tetramethylphenol

: 40123-24-8
3-Phenyl-propionic acid 2,3,5,6-tetramethyl-phenyl ester

: C₁₉H₂₁BrO₂

: C₂₈H₃₀O₃

Guidance literature:: With iodine(I) bromide; In dichloromethane; at -17 ℃; for 0.25h;
DOI:10.1055/s-0040-1707289

Reference yield:

: 22002-36-4
2,6-bis(hydroxymethyl)-3,5-dimethylphenol

: 17362-16-2
4-bromo-2,3,5,6-tetramethylphenol

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / H₂ / Pd/C / methanol / 8 h / 20 °C

2: 96 percent / nBu₄NBr₃ / methanol; CH₂Cl₂ / 20 °C

With hydrogen; tetra-N-butylammonium tribromide; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1002/ejoc.200600030

Reference yield:

: 76716-11-5
1,3-benzenedicarboxylic acid 2-hydroxy-4,6-dimethyl-1,3-dimethyl ester

: 17362-16-2
4-bromo-2,3,5,6-tetramethylphenol

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / LiAlH₄ / diethyl ether / 24 h / 0 - 24 °C

2: 68 percent / H₂ / Pd/C / methanol / 8 h / 20 °C

3: 96 percent / nBu₄NBr₃ / methanol; CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; hydrogen; tetra-N-butylammonium tribromide; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane;
DOI:10.1002/ejoc.200600030