8-HYDROXYWARFARIN

Base Information

Chemical Name:8-HYDROXYWARFARIN
CAS No.:17834-04-7
Molecular Formula:C19H16 O5
Molecular Weight:324.333
Hs Code.:2932209090
Mol file:17834-04-7.mol

Synonyms:Coumarin,3-(a-acetonylbenzyl)-4,8-dihydroxy-(8CI); 8-Hydroxywarfarin

Suppliers and Price of 8-HYDROXYWARFARIN

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-HydroxyWarfarin
5mg
$ 320.00

Sigma-Aldrich
8-Hydroxywarfarin
10mg
$ 929.00

Medical Isotopes, Inc.
8-HydroxyWarfarin
25 mg
$ 2120.00

American Custom Chemicals Corporation
8-HYDROXY WARFARIN 95.00%
5MG
$ 774.40

American Custom Chemicals Corporation
8-HYDROXY WARFARIN 95.00%
50MG
$ 1871.10

American Custom Chemicals Corporation
8-HYDROXY WARFARIN 95.00%
1MG
$ 315.00

AHH
8-Hydroxywarfarin 98%
10g
$ 778.00

Total 11 raw suppliers

Chemical Property of 8-HYDROXYWARFARIN

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:185-187 °C
Boiling Point:519.6°Cat760mmHg
Flash Point:189.3°C
PSA：87.74000
Density:1.384g/cm³
LogP:3.31520
Storage Temp.:2-8°C
Solubility.:Acetic Acid (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

8-HydroxyWarfarin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Uses A minor CYP1A2 metabolite of R-Warfarin

Technology Process of 8-HYDROXYWARFARIN

There total 6 articles about 8-HYDROXYWARFARIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 100037-67-0
3-carbethoxy-4,8-dihydrocoumarin

: 122-57-6
1-Phenylbut-1-en-3-one

: 17834-04-7
8-Hydroxywarfarin

Guidance literature:: With 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt; In 1,4-dioxane; water; for 264h; Heating;

Reference yield:

: 81-81-2
warfarin

: 17834-04-7
8-Hydroxywarfarin

: 17834-02-5,63740-75-0,63740-80-7
6-Hydroxywarfarin

: 17834-03-6
7-Hydroxywarfarin

Guidance literature:: With NADP⁺; D-glucose-6-; In aq. phosphate buffer; dimethyl sulfoxide; at 37 ℃; for 1h; pH=7.4; Enzymatic reaction;
DOI:10.1124/dmd.113.051953

Reference yield:

: 303-38-8
2,3-Dihydroxybenzoic acid

: 17834-04-7
8-Hydroxywarfarin

Guidance literature:: Multi-step reaction with 4 steps

1: 74 percent / H₂SO₄ / 0.42 h / Heating

2: thionyl chloride / diethyl ether; benzene

3: 50 percent aq. NaOH / 1,2-dimethoxy-ethane; H₂O

4: 57 percent / 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt / dioxane; H₂O / 264 h / Heating

With sodium hydroxide; thionyl chloride; 1,4-piperazinebis(ethane sulfonic acid) 1.5-Na salt; sulfuric acid; In 1,4-dioxane; 1,2-dimethoxyethane; diethyl ether; water; benzene;