4-(4-Carboxyphenoxy)phthalic acid

Base Information

• Chemical Name: 4-(4-Carboxyphenoxy)phthalic acid
• CAS No.: 7717-74-0
• Molecular Formula: C15H10O7
• Molecular Weight: 302.24
• DSSTox Substance ID: DTXSID10394528
• Nikkaji Number: J2.561.261B
• Wikidata: Q82193972
• Mol file: 7717-74-0.mol

Synonyms:4-(4-carboxyphenoxy)phthalic acid;7717-74-0;STK360634;1,2-Benzenedicarboxylic acid, 4-(4-carboxyphenoxy)-;CBDivE_002817;Oprea1_614395;SCHEMBL6865190;DTXSID10394528;4-(4-carboxyphenoxy)-phthalic acid;CS-0110916;SR-01000109237;4-(4-carboxyphenoxy)benzene-1,2-dicarboxylic acid;SR-01000109237-1

Chemical Property of 4-(4-Carboxyphenoxy)phthalic acid

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 302.04265265
• Heavy Atom Count: 22
• Complexity: 439

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=O)O)OC2=CC(=C(C=C2)C(=O)O)C(=O)O

Technology Process of 4-(4-Carboxyphenoxy)phthalic acid

There total 3 articles about 4-(4-Carboxyphenoxy)phthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-((N-methylphthalimide)-4-oxy)benzoic acid → 4-(4-carboxyphenoxy)phthalic acid (7717-74-0)

Guidance literature:

With water; sodium hydroxide; for 24h; Reflux;

DOI:10.1016/j.polymer.2013.08.037

Reference yield:

4-nitro-N-methyl-phthalimide (41663-84-7) → 4-(4-carboxyphenoxy)phthalic acid (7717-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene; dimethyl sulfoxide / 140 - 160 °C

1.2: 6 h / 120 °C

2.1: water; sodium hydroxide / 24 h / Reflux

With water; sodium hydroxide; In dimethyl sulfoxide; toluene;

DOI:10.1016/j.polymer.2013.08.037

Reference yield:

→ 4-(4-carboxyphenoxy)phthalic acid (7717-74-0)

Guidance literature:

3,4,4'-Trimethylphenoxybenzol(IV), Eg., Cobaltacetat-tetrahydrat, NaBr, O2-Gas;

upstream raw materials:

4-nitro-N-methyl-phthalimide

Downstream raw materials:

4-(p-carboxyphenoxy)phthalic anhydride