3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione
CAS No.:77384-89-5
Molecular Formula:C11H9FN2O2
Molecular Weight:220.203
Hs Code.:
DSSTox Substance ID:DTXSID20574834
Wikidata:Q82464008

Synonyms:77384-89-5;3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione;DTXSID20574834

Suppliers and Price of 3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.06480570
Heavy Atom Count:16
Complexity:335

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C(=O)C(=CNC2=O)F

Technology Process of 3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione

There total 6 articles about 3-Benzyl-5-fluoropyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1-benzhydryl-3-benzyl-5-fluoro-1H-pyrimidine-2,4-dione

: 77384-89-5
N₃-benzyl 5-fluorouracil

Guidance literature:: With trifluorormethanesulfonic acid; In trifluoroacetic acid; at 0 ℃;
DOI:10.1021/jo0485076

Reference yield: 95.0%

: 3-Benzyl-5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidine-1-carbothioic acid S-octyl ester

: 77384-89-5
N₃-benzyl 5-fluorouracil

Guidance literature:: With diisopropylamine; In dichloromethane; for 72h;

Reference yield: 87.0%

: 13593-34-5
3-benzyl-6-chloro-5-fluoro-1H-pyrimidine-2,4-dione

: 77384-89-5
N₃-benzyl 5-fluorouracil

Guidance literature:: With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; for 4h; Ambient temperature;
DOI:10.1246/cl.1984.1573