5-Bromo-2,4-dimethoxy-6-methylpyrimidine

Base Information

• Chemical Name: 5-Bromo-2,4-dimethoxy-6-methylpyrimidine
• CAS No.: 7752-70-7
• Molecular Formula: C7H9BrN2O2
• Molecular Weight: 233.06300
• ChEMBL ID: CHEMBL388835
• DSSTox Substance ID: DTXSID30493860
• Wikidata: Q82340838
• Mol file: 7752-70-7.mol

Synonyms:5-BROMO-2,4-DIMETHOXY-6-METHYLPYRIMIDINE;7752-70-7;CHEMBL388835;SCHEMBL13485920;DTXSID30493860;AB55000

Chemical Property of 5-Bromo-2,4-dimethoxy-6-methylpyrimidine

Chemical Property:

• PSA: 44.24000
• LogP: 1.56470
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 231.98474
• Heavy Atom Count: 12
• Complexity: 147

Purity/Quality:

98%min ^*data from raw suppliers

5-BROMO-2,4-DIMETHOXY-6-METHYLPYRIMIDINE >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=NC(=N1)OC)OC)Br

Technology Process of 5-Bromo-2,4-dimethoxy-6-methylpyrimidine

There total 8 articles about 5-Bromo-2,4-dimethoxy-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2,4-dimethoxy-6-methylpyrimidine (7781-23-9) → 5-bromo-2,4-dimethoxy-6-methylpyrimidine (7752-70-7)

Guidance literature:

With potassium bromide; sodium nitrite; In acetic acid; at 20 ℃;

DOI:10.1071/CH14416

Reference yield: 29.9%

2,4-dimethoxy-6-methylpyrimidine (7781-23-9) → C7H8Br2N2O2 + C7H7Br3N2O2 + 5-bromo-2,4-dimethoxy-6-methylpyrimidine (7752-70-7)

Guidance literature:

2,4-dimethoxy-6-methylpyrimidine; With acetic acid; for 0.333333h; Heating;

With N-Bromosuccinimide; for 3h; Further stages.; Heating;

DOI:10.1021/jm0614329

Reference yield:

2,4-dichloro-6-methylpyrimidine (5424-21-5) → 5-bromo-2,4-dimethoxy-6-methylpyrimidine (7752-70-7)

Guidance literature:

Multi-step reaction with 2 steps

2: N-bromosuccinimide

With N-Bromosuccinimide;

DOI:10.1248/cpb.36.2042

upstream raw materials:

2,4-dimethoxy-6-methylpyrimidine

5-bromo-2,4-dichloro-6-methylpyrimidine

sodium methylate

2,4-dichloro-6-methylpyrimidine

Downstream raw materials:

2,4-dimethoxy-6-methyl-5-phenylpyrimidine

(E)-β-(2,4-Dioxo-6-methyl-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid

5-carboxy-2,4-dimethoxy-6-methylpyrimidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 7752-70-7 5-BROMO-2,4-DIMETHOXY-6-METHYLPYRIMIDINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send