(1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone

Base Information

Chemical Name:(1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone
CAS No.:77832-96-3
Molecular Formula:C21H13BrClNO2
Molecular Weight:426.697
Hs Code.:
DSSTox Substance ID:DTXSID20539483
Wikidata:Q82415252

Synonyms:77832-96-3;DTXSID20539483;(1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone

Suppliers and Price of (1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone

Chemical Property:

XLogP3:6.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:424.98182
Heavy Atom Count:26
Complexity:512

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N3C=CC=CC3=C2Br)C(=O)C4=CC(=C(C=C4)O)Cl

Technology Process of (1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone

There total 2 articles about (1-Bromo-2-phenylindolizin-3-yl)(3-chloro-4-hydroxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Toluene-4-sulfonic acid 4-(1-bromo-2-phenyl-indolizine-3-carbonyl)-2-chloro-phenyl ester

: 77832-96-3
(1-Bromo-2-phenyl-indolizin-3-yl)-(3-chloro-4-hydroxy-phenyl)-methanone

Guidance literature:: With sodium hydroxide; In methanol; acetone; for 21h; Yield given; Heating;

Reference yield:

: 88273-87-4
Toluene-4-sulfonic acid 2-chloro-4-(2-phenyl-indolizine-3-carbonyl)-phenyl ester

: 77832-96-3
(1-Bromo-2-phenyl-indolizin-3-yl)-(3-chloro-4-hydroxy-phenyl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: Br₂, sodium acetate trihydrate / dioxane / 1.5 h / 20 - 30 °C

2: 30percent sodium hydroxide / methanol; acetone / 21 h / Heating

With sodium hydroxide; bromine; sodium acetate; In 1,4-dioxane; methanol; acetone;