N-[4-(2-Nitroacetyl)phenyl]acetamide

Base Information

Chemical Name:N-[4-(2-Nitroacetyl)phenyl]acetamide
CAS No.:77901-53-2
Molecular Formula:C10H10N2O4
Molecular Weight:222.2
Hs Code.:
DSSTox Substance ID:DTXSID201290800

Synonyms:N-[4-(2-Nitroacetyl)phenyl]acetamide;SCHEMBL8752484;DTXSID201290800;77901-53-2

Suppliers and Price of N-[4-(2-Nitroacetyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[4-(2-Nitroacetyl)phenyl]acetamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:222.06405680
Heavy Atom Count:16
Complexity:290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C(=O)C[N+](=O)[O-]

Technology Process of N-[4-(2-Nitroacetyl)phenyl]acetamide

There total 3 articles about N-[4-(2-Nitroacetyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 75-52-5
nitromethane

: 556-08-1
p-(acetylamino)benzoic acid

: 77901-53-2
N-(4-(2-nitroacetyl)phenyl)acetamide

Guidance literature:: With triethylamine; diethyl dicarbonate; In N,N-dimethyl-formamide; 0 deg C, 2 h, RT, 20 h;
DOI:10.1248/cpb.29.259

Reference yield:

: 75-52-5
nitromethane

: 92577-27-0
1-(4-acetylamino-benzoyl)-1H-imidazole

: 77901-53-2
N-(4-(2-nitroacetyl)phenyl)acetamide

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1039/c9ob00051h

Reference yield:

: 556-08-1
p-(acetylamino)benzoic acid

: 77901-53-2
N-(4-(2-nitroacetyl)phenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 1 h

2: potassium tert-butylate / tetrahydrofuran / 24 h / 20 °C

With potassium tert-butylate; In tetrahydrofuran;
DOI:10.1039/c9ob00051h